RCSB PDB is an organization that operates the Protein Data Bank, an archive of information about the 3D shapes of proteins, nucleic acids, and complex assemblies that helps researchers understand the details of molecular interactions and biological processes. The resource is essential for scientific research and education in the fields of biology, bioinformatics, and medicine.

RCSB Protein Data Bank

RCSB PDB

The Protein Data Bank (PDB) was established in 1971 as the 1st open access digital data resource in all of biology and medicine. It is today a leading global resource for experimental data central to scientific discovery.

Through an internet information portal and downloadable data archive, the PDB provides access to 3D structure data for large biological molecules (proteins, DNA, and RNA). These are the molecules of life, found in all organisms on the planet.

Knowing the 3D structure of a biological macromolecule is essential for understanding its role in human and animal health and disease, its function in plants and food and energy production, and its importance to other topics related to global prosperity and sustainability.

RCSB PDB operates the US data center for the global PDB archive, and makes PDB data available at no charge to all data consumers without limitations on usage.

The Vision of the RCSB PDB is to enable open access to the accumulating knowledge of 3D structure, function, and evolution of biological macromolecules, expanding the frontiers of fundamental biology, biomedicine, and biotechnology.

Recognized experts in fields, including but not limited to, structural biology, cell and molecular biology, computational biology, information technology, and education serve as advisors to the RCSB PDB.

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Celebrating 20 Years of the wwPDB by announcing the launch of Protein Data Bank China (PDBc) as an Associate Member of the Partnership 
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Meet the RCSB PDB at ACA
Join us for posters, presentations, and more at the annual meeting of the American Crystallographic Association (July 7-11). 
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As structures of protein kinases were determined, it was found that their ATP-binding pockets had large enough differences that facilitated the structure-guided discovery and development of selective drugs. The anti-cancer drug imatinib was the breakthrough success. Since then, great strides have been made toward the successful development of selective small-molecule inhibitors for various protein kinases, many being the products of structure-guided drug discovery.  More at Molecule of the Month

DNA can mimic protein functions by folding into elaborate, three-dimensional structures
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Explore the Structural Biology of Bioenergy: 
Visit PDB-101 to learn how cells capture and utilize many forms of energy to power their molecular processes
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Toggle to "Opt-in" to Access Computed Structure Models Alongside PDB Data: Move the slider to use RCSB PDB tools with >1 million CSMs from AlphaFold and ModelArchive
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PDB-101's Guide to Understanding PDB Data helps non-experts navigate through the PDB. A new chapter introduces the APIs that query and deliver PDB data at RCSB.org.
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June 14 is #worldblooddonorday2023 
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Watch the Crash Course: Understanding PDBx/mmCIF
Learn about PDBx/mmCIF basics, software tools for generating and working with PDBx/mmCIF files, and programmatic access for harvesting data
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