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BCMA-Targeted CAR-T Cell Therapy Progress
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Nexcella and Immix Biopharma both present updated data from their Phase 1b/2 clinical trials of BCMA-targeted CAR-T cell therapies, NXC-201, at the 20th International Myeloma Society Annual Meeting. NXC-201 shows promising results in multiple myeloma, with 72% overall response rate. Both companies plan to submit data to the FDA for multiple myeloma and AL amyloidosis once 100-30 patients are treated. Nexcella also completes its 2nd engineering batch of NXC-201 at its U.S. manufacturing site, aiming to expand clinical trial to the United States.
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How might the FDA's approval of NXC-201 impact the market for CAR-T cell therapies?
How might the completion of the 2nd engineering batch of NXC-201 impact the development and accessibility of BCMA-targeted CAR-T cell therapies?
What are the potential challenges and implications of expanding clinical trials for BCMA-targeted CAR-T cell therapies to the United States?
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