Iambic Therapeutics develops AI-driven platforms for drug discovery, focusing on optimizing medicines for specific disease profiles and addressing unmet patient needs. The company self-describes its approach as innovative and efficient.

Iambic Therapeutics

Cradle Fund is focused on empowering early stage startups through various programmes and initiatives, including monetary aid, commercialisation support, and additional value-added services to accelerate growth.

Cradle Fund

Atomwise is a preclinical pharma company revolutionizing drug discovery with AI. They have invented the use of deep learning for structure-based drug discovery and are developing a pipeline of small-molecule drug candidates. Their AtomNet® technology has been used to unlock more undruggable targets than any other AI drug discovery platform. Atomwise is tackling over 600 unique disease targets with more than 250 partners around the world, including leading pharmaceutical, agrochemical, and emerging biotechnology companies.

Izhar Wallach

Alexander Levy

Abraham Heifets

Atomwise

10x Genomics, Inc., a life science technology company, develops and sells instruments, consumables, and software for analyzing biological systems in North America, Europe, the Middle East, Africa, China, and the Asia Pacific. The company provides chromium and chromium connect instruments, microfluidic chips, slides, reagents, and other consumables products. Its single cell solutions runs on its chromium instruments, which include single cell gene expression for measuring gene activity on a cell-by-cell basis; single cell immune profiling for measuring the activity of immune cells and their targets; single cell Assay for Transposase Accessible Chromati (ATAC) for measuring epigenetics comprising the physical organization of DNA; and single cell multiome ATAC + gene expression for measuring the genetic activity and epigenetic programming in the same cells across tens of thousands of cells in a single experiment. The company also provides visium spatial gene expression solution for measuring spatial gene expression patterns across a single tissue sample or gene expression and protein co-detection when combined with immunofluorescence. It serves various academic, government, biopharmaceutical, biotechnology, and other institutions. The company was formerly known as 10X Technologies, Inc. and changed its name to 10x Genomics, Inc. in November 2014. 10x Genomics, Inc. was incorporated in 2012 and is headquartered in Pleasanton, California.

Ben Hindson

Serge Saxonov

10x Genomics, Inc.

Iambic Therapeutics is disrupting the therapeutics landscape with its unique AI-driven drug-discovery platform. Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters with strong track records of success in delivering clinically validated therapeutics. The Iambic platform has been demonstrated to deliver high-quality, differentiated therapeutics to clinic with unprecedented speed and across multiple target classes and mechanisms of action. The Iambic team is advancing an internal pipeline of clinical assets to address urgent unmet patient needs. Learn more about the Iambic team, platform, and pipeline at iambic.ai.

Join Sayan Mondal, Iambic Therapeutics Executive Director of Computational Chemistry and Co-Chair of the PDDP Summit, in a panel discussion on pioneering the biopharma landscape with Al-driven drug discovery and development. Precision Evolution Global

Date/time: October 13th, 12:10pm - 1:15pm PT

#drugdiscovery #artificialintelligence #machinelearning

Tune into Iambic co-founder and CEO Thomas Miller discussing the genesis and future of Iambic on BIOS!

Iambic Therapeutics (formerly known as Entos) announced the closing of its oversubscribed $100 million Series B financing round to advance AI-discovered therapeutics into clinical development. Concurrently, Iambic has entered a collaboration with NVIDIA to leverage NVIDIA technology to accelerate drug discovery. 

Said CEO Thomas Miller, “At Iambic, our world-class team has combined physics and AI to create a differentiated drug discovery platform that achieves a step-change in the speed and success rate for delivering best-in-class and first-in-class development candidates to clinic.” 

The funding will be used to advance multiple candidates into clinical development (including a selective brain-penetrant HER2 inhibitor and a selective dual CDK2/4 inhibitor), expand its pipeline with additional candidates, and build next-generation AI and automation technologies for drug discovery. 

The new name of Iambic Therapeutics reflects its transition to a company with the additional capability of clinical development of candidates identified through its AI-driven discovery platform.  

We’re proud to support this innovative company and welcome Iambic Therapeutics to the Illumina Ventures portfolio.  

Read the full press release: https://lnkd.in/ex3JkGZY

Ascenta Capital 
Abingworth 
NVIDIA
Gradiant Corporation 
Nexus Venture Partners
Catalio Capital Management 
Coatue 
Freeflow Ventures
OrbiMed 
Sequoia Capital

Ron Mazumder 
Charles Lin
Bill Rastetter

HomeLab™ at UC San Diego

#PartnerNews #MachineLearning #AI #ArtificalIntelligence #DrugDiscovery #Healthcare #SanDiego

Hearty congrats to Thomas Miller, Fred Manby, and team Iambic Therapeutics (formerly known as Entos), on securing their Series B round. We are thrilled to have partnered with them from 2020, when we led their seed round, and are delighted to have participated in this round alongside a group of stellar investors. 

We eagerly look forward to Iambic’s continued growth and success as they disrupt the therapeutics landscape with their unique generative AI-driven drug-discovery platform.

Jishnu B. I Nexus Venture Partners I #NexusVP

https://lnkd.in/ex3JkGZY

Iambic Therapeutics (previously #Entos) has successfully closed an oversubscribed $100 million Series B financing round, co-led by Ascenta Capital and Abingworth, with participation from new and existing investors including NVIDIA, #IlluminaVentures, and Sequoia Capital. 

These funds aim to bolster the development of their pioneering AI-driven drug discovery platform and advance several AI-identified therapeutic candidates. With a combined expertise in physics and AI, Iambic strives to revolutionize drug discovery. https://lnkd.in/eymxF8TF

Entos is now Iambic Therapeutics! We are excited to announce that Iambic has closed a $100 Million Series B to continue work on advancing AI-discovered therapeutics into clinical development as we enter a collaboration with NVIDIA.

This funding, co-led by Ascenta Capital and Abingworth, will support new AI platform innovations, advancement of multiple candidates into clinical development, and expansion of internal pipeline  across target classes and therapeutic areas.

Read the full press release at: https://lnkd.in/ex3JkGZY

#DrugDiscovery #ArtificialIntelligence #MachineLearning

Entos co-founder and CEO Thomas Miller joined the AI in Drug Discovery panel at #IDSD23, discussing clinical drug candidates created using the Entos AI-driven drug-discovery platform. A big thanks to Aiden Aceves, Ph.D. at Insight Partners for moderating and Connect for coordinating!

#DrugDiscovery #MachineLearning #AI

We are thrilled to see Entos included in Insider's list of most-promising healthcare start-ups of 2023 for accelerating the delivery of new drugs to clinic with our AI-driven high-throughput drug-discovery platform.

https://lnkd.in/e7MbKMb3

#artificialintelligence #healthcare #machinelearning #drugdiscovery

Join Entos CEO Thomas Miller at the The Camille and Henry Dreyfus Foundation/American Chemical Society Symposium on Machine Learning to learn about advances in AI-driven drug discovery!

Date: Tuesday, August 15, 3pm PT

https://lnkd.in/eZ4_C3Pg

#ACSFall2023 #machinelearning #drugdiscovery #artificialintelligence

Metric
Company Name	Iambic Therapeutics	Cradle Fund	Atomwise	10
Symbol				TXG
MSH ID	AI:IAMBIC	MY:COM:CRADLE	COM:ATOMWISE	COM:10XGENOMICS
Market	PRIVATE	PRIVATE	PRIVATE	STOCKS
Sector	Healthcare & Health Services	Financial Services & Finance	Healthcare	Healthcare
Industry	Biotechnology	Venture Capital	Pharmaceuticals	Medical - Healthcare Information Services
Country	US	MY	US	US
Stage				Post-IPO
Employee Count	59		73	1.26K
Website	iambic.ai	cradle.com.my	atomwise.com	10xgenomics.com
LinkedIn			atomwise	10xgenomics
Founders

Metric
Market Cap		1.88B
Enterprise Value
Monthly Web Traffic	3.40K	150.48K
Web Traffic Growth	1.28	-0.39
Valuation
Raised Capital	1M

Metric
Revenue				618.73M
Revenue (LTM)
Revenue (NTM)
Gross Profit				409.31M
EBITDA				-158.25M
Operating Income				-201.87M
Net Income				-255.10M
EPS				-2.18
Diluted EPS				-2.18
Revenue 2022
Revenue 2023
Revenue 2024
Revenue 2025
Revenue 2026

Metric
Revenue Growth (LTM)
Revenue Growth (NTM)
Gross Profit Growth (LTM)
EBITDA Growth (LTM)
Net Income Growth (LTM)
14-Day Growth Score
28-Day Growth Score
90-Day Growth Score
365-Day Growth Score

Metric
Gross Profit Margin				0.65
Operating Profit Margin				-0.37
EBITDA Margin				-0.26
Net Profit Margin				-0.38
Return on Equity				-0.33
Return on Assets				-0.26
Return on Capital Employed				-0.28

AI:IAMBIC

Iambic Therapeutics

Company Overview

Market Metrics

Financial Performance

Growth Metrics

Profitability Ratios

Valuation Multiples

Operational Metrics

Cash Flow Metrics

Balance Sheet Metrics

Efficiency Metrics

Metric
P/E Ratio				-22.67
P/B Ratio				6.79
Revenue Multiple (LTM)
Revenue Multiple (NTM)
EBITDA Multiple (LTM)
EBITDA Multiple (NTM)
Price to Sales Ratio				7.04
EV Multiple				-9.56

Metric
Days Sales Outstanding				64.14
Days Payables Outstanding				38.61
Days Inventory Outstanding				141.51
Operating Cycle				194.20
Cash Conversion Cycle				164.30
Asset Turnover				0.68

Metric
Operating Cash Flow				-15.20M
Free Cash Flow				-64.72M
Cash Flow to Debt				-0.09
Operating Cash Flow/Sales				-0.01
Free Cash Flow Yield				-0.02

Metric
Cash & Equivalents				359.28M
Accounts Receivable				-10.61M
Inventory				73.71M
Goodwill				4.51M
Debt to Capitalization				0.11
Debt to Assets				0.10
Current Ratio				5.37
Quick Ratio				4.45

Metric
Rule of 40 (LTM)
Rule of 40 (NTM)
Stock Comp to Revenue				0.29
R&D to Revenue				0.52
SG&A to Revenue