Akouos, Inc., a precision genetic medicine company, developing gene therapies to restore, improve, and preserve physiologic hearing for individuals. The company's precision genetic medicine platform incorporates a proprietary adeno-associated viral vector library and a novel delivery approach. Its lead product candidate is AK-OTOF, a gene therapy for the treatment of hearing loss due to mutations in the OTOF gene. The company is also developing AK-CLRN1 for the auditory manifestations of Usher syndrome 3A, or USH3A; and AK-antiVEGF for vestibular schwannoma. In addition, its precision genetic medicine platform addresses hearing loss related to genes needed for supporting cell function. The company was incorporated in 2016 and is based in Boston, Massachusetts.

Akouos, Inc.

Surveyor Capital

Wu Capital

Cormorant Asset Management

Fidelity Management and Research Company

Novartis Venture Fund

Pivotal bioVenture Partners

Polaris Founders Capital

RA Capital Management

New Enterprise Associates

Akouos

We love spooky season! Check out these scenes from last month's Halloween party. Costumes were encouraged, and our team members showcased their incredible creativity.
 
The Best Costume Award went to Grace Cook, Samantha Davis took home the Most Original Costume Award, and Heather Devantier won the "I Wish I Had Thought of That" Award! Many thanks to all who participated and made the day so fun!
 
If you’re interested in joining the Akouos family, we encourage you to visit https://lnkd.in/g5w8FE6t to browse our current job openings and apply online.
 
#TeamAkouos #Halloween

Even the rain couldn’t keep the fun away! Members of our team and their families got together for a memorable fall outing at Kimball Farm. The team connected over a meal and drinks, ice cream, and some exhilarating bumper car action. Thank you to each and every one of you who came out to spend time together! Looking to be part of the Akouos team? Click the link below to explore our career opportunities!

#TeamAkouos

https://lnkd.in/g5w8FE6t

Celebrate the power of STEM with us this National STEM Day! Our mission of making healthy hearing available to all drives us forward every day. If you're looking for an opportunity to work on cutting-edge projects and contribute to meaningful advancements in medicine, explore our career openings and consider joining our dynamic team: https://lnkd.in/g5w8FE6t

#NationalSTEMDay #STEMDay #STEMImpact #STEMCommunity

Earlier this month, the Akouos team participated in the #Walk4Hearing! Each year we are honored to walk in solidarity with the deaf and hard of hearing community as we share our commitment to our mission to make healthy hearing available to all.

Click through to see some memories from this year’s walk and years past!


#NEWalk4Hearing

Akouos is excited to attend the 30th Annual European Society of Gene and Cell Therapy (ESGCT) Congress in Brussels, Belgium. We look forward to connecting with experts from around the world at these two engagements:

Aaron Tward, Chief Scientific Officer, will be presenting an update on “Considerations in the Development of a Gene Therapy for Otoferlin Gene-mediated Hearing Loss.”

Additionally, Katherine Gribble will be presenting on "The Efficiency of Multiplexing Guide RNAs for Multi-gene CRISPR/CaS9-based Genomic Modulation" at P696 during the poster sessions.
 
#ESGCT
 

	Dec '18	Dec '19	Dec '20	Dec '21
revenue
cost of revenue
gross profit
selling and marketing expenses
general and administrative expenses	1.78M -	3.41M 92.00%	14.58M 327.65%	22.23M 52.41%
selling general and administrative expenses	1.78M -	3.41M 92.00%	14.58M 327.65%	22.23M 52.41%
research and development expenses	5.64M -	20.47M 262.74%	34.30M 67.52%	64.59M 88.34%
other expenses
cost and expenses	7.42M -	23.88M 221.87%	48.88M 104.66%	86.82M 77.62%
operating expenses	7.42M -	23.88M 221.87%	48.88M 104.66%	86.82M 77.62%
interest expense
ebitda	-5.96M -	-25.04M 320.34%	-46.42M 85.37%	-82.92M 78.62%
operating income	-7.42M -	-23.88M 221.87%	-48.88M 104.66%	-86.67M 77.31%
depreciation and amortization	55K -	697K 1,167.27%	2.17M 212.05%	3.75M 72.28%
total other income expenses net	1.41M -	-1.86M 232.05%	280K 115.07%	150K 46.43%
income before tax	-6.01M -	-25.74M 328.09%	-48.60M 88.80%	-86.67M 78.34%
income tax expense	1.41M -	-1.86M 232.05%	280K 115.07%	150K 46.43%
net income	-6.01M -	-25.74M 328.09%	-48.60M 88.80%	-86.67M 78.34%
weighted average shs out	6.43M -	6.43M 0%	17.55M 172.76%	17.55M 0%
weighted average shs out dil	6.43M -	6.43M 0%	17.55M 172.76%	17.55M 0%
eps	-0.93 -	-4 330.11%	-2.77 30.75%	-4.94 78.34%
epsdiluted	-0.93 -	-4 330.11%	-2.77 30.75%	-4.94 78.34%

COM:AKOUOS

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