Alltrna is the first transfer RNA (tRNA) platform company, and our mission is to unlock tRNA biology and pioneer tRNA therapeutics to regulate the protein universe and resolve disease. Founded at Flagship Labs in 2018, Alltrna has mapped tRNA biology to systematically design tRNA medicines and encode a completely new, unifying approach to treating both rare and common human diseases driven by shared genetic mutations. Alltrna’s platform combines internal expertise and proprietary machine learning tools to unlock the entire tRNA biology space. We have an unprecedented opportunity to advance a single tRNA medicine to restore disrupted protein production, regardless of target, for thousands of diseases with the same underlying genetic mutation.

Flagship Pioneering

Alltrna

We’re thrilled to announce our Series B financing of $109 million with a world-class group of investors. This financing will support further scaling of our platform and advancing our first #tRNA medicines to clinical trials as we build a new future for patients with #StopCodonDisease.

Read the release here: https://lnkd.in/gJcC65nx

#financing #biotech #Boston

Our CEO Michelle Werner spoke with Ray Dogum at Vibe Bio about the unique ability of #tRNA medicines to potentially treat thousands of #rarediseases which share the same genetic mutations.

Learn more about #StopCodonDisease and #tRNA biology on this #VibeCast episode: https://lnkd.in/gYTrxRuh

At Alltrna, health and well-being is something we prioritize for our employees. We took a synchronous #summerbreak the first week of July, knowing that this time away fosters creativity and rejuvenation. Check out the video showcasing the fun experiences of our team during their time off. We know that our commitment to patients is best fulfilled when we take care of ourselves as well.

#EmployeeWellness #WorkLifeBalance #Innovation #WeAreAlltrna

For #DisabilityPrideMonth, our CEO Michelle Werner writes about how helping her son, who has #Duchenne #musculardystrophy, navigate the world made it clear why accessibility is necessary to creating inclusive and diverse cultures. #AlltrnaForAll #culture #diversityandinclusion #workplacediversity #accessibility

We are excited to share this quarter’s #EmployeeSpotlight featuring Derrick Allen, one of our senior scientists. Derrick’s specialty lies in analysis, which he likens to figuring out a puzzle. At Alltrna, he has helped build the CMC lab and team from scratch and is motivated daily by the drive to ensure quality in our data to drive better patient outcomes.

If you are interested in building a bold new future for patients, check out our #openpositions: https://lnkd.in/ghQQGi3s

#wearehiring #joinus #tRNA #tRNAbiology #tRNAmedicines #tRNAtherapeutics #programmablemedicines

For our first day of service, our team members volunteered at Cradles to Crayons Massachusetts and Community Servings. It was rewarding giving back to our community and supporting those in need. At Alltrna, our values guide us every step of the way. We give it our all, every day – in and outside the office! #WeAreAlltrna

For our first day of service, our team members volunteered at Cradles to Crayons Massachusetts and Community Servings. It was rewarding giving back to our community and supporting those in need. At Alltrna, our values guide us every step of the way. We give it our all, every day – in and outside the office! #WeAreAlltrna.

This week our CEO, Michelle Werner, contributed to an impactful #BIO2023 panel discussing leadership advantages women bring to the C-suite. The panel's key takeaway: women possess not just soft skills like empathy and inclusion, but they unequivocally deliver results and act as catalysts. Michelle is definitely a catalyst, and we are proud to have her leading Alltrna!

#WomenInLeadership #WomenInBiopharma

Next week our CEO Michelle Werner will be in-person at the #LongwoodHealthcareLeaders conference discussing accelerating the path to patient care on a panel with execs from Moderna, Akili Labs, Karyopharm Therapeutics Inc., and Galera Therapeutics, Inc.  

See the full agenda for Longwood Healthcare Leaders Spring MIT Conference: https://lnkd.in/e4AhEbXp

#tRNA #rarediseases #cancer #tRNAmedicines #tRNAtherapeutics

We are delighted to share that our CEO Michelle Werner will be joining other high-profile female #BioPharmaLeaders for a candid discussion on how to lead the industry through the bear market with high-risk decision making, emotionally intelligent leadership, resilience, and collaboration. 

More info: https://lnkd.in/gkRkgKjE

#WomenInLeadership #BIO2023 #BiopharmaLeadership #Innovation #WomenInSTEM

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Senior Vice President, Therapeutic Development and Pipeline Strategy at Alltrna

Nikolai Naryshkin

Finance and Administration

Andrew Choly

Information Technology

Erwin Irdam

Marketing and Product

Harsh Chauhan

Associate Director Medicinal Chemistry

Hongchuan Yu

Healthcare

Isabelle Sansal

Director of Strategy & Operations

Taleen Afeyan

Adam Darkazalli

Senior Manager Program Management

Jessica Bauer

Senior Manager, Lab Operations

Mojgan Pishyareh

Anne Pariser

VP, Medical and Regulatory Affairs

Joanne Protano

Chief Financial Officer

Lovisa Afzelius

Founding CEO and Director

Theonie Anastassiadis

Co-founder and Chief Innovation Officer

Cambridge Companies With More Than $10M in Revenue

East Coast Early Stage Companies With Fewer Than 100 Employees

East Coast Therapeutics Female Founded Companies

Northeastern US Biotechnology Female Founded Companies

Alltrna is the tRNA platform company to decipher tRNA biology and pioneer tRNA therapeutics to treat thousands of diseases. tRNAs play a central role in the translation of mRNA into proteins.  tRNA biology modulates the complex code of DNA and RNA across translation and transcription. Altrna platform incorporates AI/ML tools to learn the tRNA language and deliver diverse programmable molecules with broad therapeutic potential.

Series B - Alltrna

Venture Round - Alltrna

Cambridge

Massachusetts

United States

North America

Alltrna Announces Updates to Its Board of Directors

Alltrna Applies Machine Learning to Engineer tRNA Oligonucleotides with Significantly Improved Activity and ...

World Changing Ideas 2024: Science and technology honorees

Alltrna Pioneers New Processes to Synthesize Chemically Modified tRNAs

Alltrna Announces Presentations at ASGCT 27th Annual Meeting and TIDES USA 2024

Alltrna's platform uses machine learning to design optimized tRNA molecules for treating diseases with genetic mutations.

The company designs tRNA molecules to have therapeutic properties by exploring tRNA sequences and modifications.

Alltrna tests designed tRNA molecules for desired features using automated assays and animal models.

Data from tRNA molecule testing is integrated into Alltrna’s platform to improve predictions for designing therapeutic tRNAs.

Alltrna has developed tRNA medicines that can read stop codons and restore full-length protein production, aiming to treat thousands of diseases.

Sweden

Europe

Germany

Estonia

AllTRNA is a leading online platform that provides comprehensive information and resources about transfer RNA (tRNA). It offers a wide range of educational content, research articles, and tools to help scientists, researchers, and students understand the role and functions of tRNA in protein synthesis.

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