BioProcess International is a publication that provides insights and information related to the bioprocessing industry. It covers upstream and downstream processing, manufacturing, analytical techniques, and business aspects in biotech.

BioProcess International

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BioProcess International Academy

BioProcess International | 24,299 followers on LinkedIn. brought to you by Informa Connect | BioProcess International™ is a monthly, controlled-circulation magazine devoted to the development, scale-up, and manufacture of biotherapeutics and biodiagnostics. Each issue provides the global industrial biotherapeutic community with up-to-date, peer-reviewed information detailing the business, politics, ethics, applications, products, and services required to successfully drive biopharmaceuticals, vaccines, and biodiagnostics through the development and manufacturing process. 
BPI is a business unit of Informa Connect https://informaconnect.com

Biologics Analytical CMC and Lab Quality R&D to GMP

Nadine M. Ritter, Ph.D.

Retired

Maribel Rios

TKH Bioconsult LLC

Timothy Hayes

Associate Editor at BioProcess International

Alison Center

That's a wrap on our BioProcess International Conference & Exhibition 2024 in Boston! Aside from our enhanced onsite features including coffee baristas, daily live music, wine & cheese, lobster rolls, masseuse, manicurist, comfort seating, work pods, and charging ports in all session rooms, this year's event featured: ✓ 3200+ bioprocessing professionals from 36 countries ✓ All top 20 largest biopharma companies ✓ 100+ startups ✓ 340+ industry leading speakers across 9 tracks ✓ 220+ exhibitors supporting the entire bioprocessing spectrum ✓ Offsite networking party at Museum of Science Check out the latest highlights from this year's event! #biotechweekboston #BPIevent #CellGeneEvent #bioprocessing

Please join us for a #BPIAskTheExpert on "Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges." Multimodal #chromatography has a history of providing value for #biopharmaceutical separations. Ligands that enable binding based on both charge and #hydrophobic interactions provide more opportunity for effective separation of multiple product- and process-related impurities. However, more diverse protein therapeutics and evolving expression systems present separation challenges that may not be easily addressed by commercially available multimodal resins. This #webinar will discuss several molecules that were prioritized for high-throughput evaluation of Nuvia wPrime 2A Resin, including an IgG1 monoclonal antibody ( #mAb ), IgG4 mAb, and a bispecific antibody ( #bsAb ), with extra focus placed on proteins with low isoelectric points (pI) and known strong binding to alternative MMAEX resins. Date: Thurs., November 14th. Time: 11 AM ET. Featuring: Michael Rauscher , Associate Principal Scientist, Process R&D Enabling Technologies, Merck . Register Now: https://lnkd.in/gsEG7Wjh

Please join us for a #BPIAskTheExpert on "AAE-MS™: A Powerful Method to Assess Host Cell Protein ELISA Fit for Purpose." Antibody Affinity Extraction (AAE) is a powerful orthogonal approach to determine if a host cell protein (HCP) ELISA is fit for purpose. AAE is referenced as immunoaffinity #chromatography in USP 1132 and has been used in over 300 projects to perform antibody coverage analysis for regulatory submissions. This #webinar will focus on several case studies demonstrating utility of AAE-MS method in identification of immunoreactive HCPs to establish HCP antibody coverage, HCPs enriched during process changes, and HCPs co-purified with DS. Date: Tues., November 12th. Time: 11 AM ET. Featuring: Jared Isaac, PhD MBA , Associate Director, Chromatography and Mass Spectrometry, Cygnus Technologies, LLC . Register Now: https://lnkd.in/gZNZEFkX

Please join us for a #BPIAskTheExpert on "Out of the Box Computer Software Assurance with ValGenesis VLMS." Computer software assurance (CSA) allows for faster deployment of your #validation needs compared to traditional computer systems validation (CSV). In this #webinar , learn how you can utilize modern methodologies and digital technologies such as ValGenesis’ VLMS to adapt your current CSV practices into CSA to streamline your validation process. Date: Thurs., November 7th. Time: 11 AM ET. Featuring: Jeff R. , Solutions Engineer, ValGenesis . Register Now: https://lnkd.in/ghsVfBxC

We've had the great opportunity to speak to Eric Halioua , CEO of PDC*line Pharma , on the company’s journey from its inception to its current breakthroughs in cancer immunotherapies. Eric shared insights on the drive behind PDC*line Pharma's unique platform, the resilience required to push forward in biotech, and the impact of global partnerships. Stay tuned for more on how PDC*line Pharma is advancing clinical trials and what we can expect to hear from them at Cell and Gene Therapy International Europe, this December! Read more below: #cellandgenetherapy #biotech #bioprocessing

Please join us for a #BPIAskTheExpert on "Introduction to Lonza CHO Media Portfolio: Harnessing Simplicity with the TheraPRO® CHO Media System." The growing field of #antibody #therapeutics is revolutionizing #healthcare by offering more precise treatments for various diseases. This advancement demands that #pharmaceutical companies efficiently produce high-quality proteins in large volumes. In this webinar, Sanjay Kumar, PhD will discuss Lonza’s CHO media portfolio, with a focus on the TheraPRO® GS CHO media system, highlighting key attributes and sharing compelling data generated with this system. Date: Thurs., October 31st. Time: 11 AM ET. Featuring: Sanjay Kumar , PhD, Head of Technical Excellence, Media Solutions, Lonza Bioscience Media Solutions. Register Now: https://lnkd.in/gACTW4AG

Be sure to check out our latest October 2024 issue of BioProcess International on downstream processing - available in print and digital! This issue features fascinating articles from talented professionals. Read on for a preview of the articles linked below: From the Editor: October 2024 by Cheryl Scott . The Crucial Role of Artificial Intelligence in Enhancing Clinical Outcomes by Ofer Sharon . Overcoming Scalability Barriers To Advance Cell Therapies in Development: CDMOs Can Be the Key to Success by Andy Lewin & Lior Raviv . Next-Generation Laboratory Moves: Strategies To Maximize Your Laboratory-Relocation Plan by Jasmina Xie. Influence of Air-Diffusion Value Shifts on Virus-Clearance Values: Safety Risk Assessment for Virus-Filter Integrity Testing in Multiround Housings HYEJEE JANG , Lalit Saxena , Seonmi Kim, Jihyun Lee , & Yonghwan Jin . Safeguarding Bioproduction Modalities: Comprehensive Testing Strategies Require Reliable Analytical Processes and Reference Materials by Leka Papazisi & Fang Tian . Lessons in Bioreactor Scale-Up, Part 4: Physiochemical Factors Affecting Oxygen Transfer and the Volumetric Mass-Transfer Coefficient in Stirred Tanks by Muhammad Arshad Chaudhry. Single-Use Devices for Alternating Tangential-Flow Filtration: Highly Efficient Perfusion Processes Over 50 Days (Webcast Recap) by Jan Ott . Enabling CDMOs To Focus on Their Core Priorities: Outsourcing Supply-Chain and Buffer-Preparation Activities by César Mauras . Beyond ELISA: Is Mass Spectrometry the Future of Impurity Analysis? by Thomas Kofoed , Margarita Sabater , Bryant McLaughlin , Søren Skov Jensen . Advanced Characterization of HCP Polyclonal Antibodies: Combining Antibody Affinity Extraction and Mass Spectrometry by Alla Zilberman , Jared Isaac, PhD MBA , & Eric Bishop . Fighting Neurodegenerative Diseases: The Need for Combination Biologics by Howard Berman, PhD . #downstreamprocessing #artificialintelligence #celltherapies #supplychain Follow the link below to read the full issue: https://lnkd.in/g4KQh3Xf

Please join us for a #BPIAskTheExpert on "Introducing Super Refined™ Poloxamer 188: Optimized for Mammalian Cell Culture with Exceptional Batch-to-Batch Consistency." Poloxamer 188 is a surfactant with a longstanding history of use in #pharmaceutical drugs, spanning dosage routes from oral to topical and parenteral administration. In the #biomanufacturing space, it finds application not only as a surfactant for parenteral biological formulations, but also in #cellculture as a shear stress protectant. Join this #webinar to understand exceptional performance in cell viability performance against competitor materials in both #CHO and #HEK suspension lines, analyze data highlighting batch-to-batch consistency in performance along with supporting #analytical data on the poloxamer compositional and impurity profile. Date: Tues., October 29th. Time: 11 AM ET. Featuring: James Humphrey, Research and Technology Specialist, Garima Sinha Lead Applications Scientist, Jessica Santa Maria, Technical Marketing Lead, Croda Pharma Register Now: https://lnkd.in/giQhCPCP

Please join us tomorrow for a #BPIAskTheExpert on "What if Your Supply Chain forSingle-Use Equipment Was Robust?" The #pandemic should have taught us that dual or multi-sourcing helps to strengthen #supplychains . But did you know that the implications for manufacturers and #CDMOs are even greater? Join this #webinar to learn more about the possibilities of using vendor-independent components for your #biopharmaceutical fluid path. Date: Thurs., October 24th. Time: 11 AM ET. Featuring: David Seifert , Head of Sales Application Engineering Sterile Consumables & Khalil Essani , Product Line Manager, Sterile Consumables, Single Use Support . Register Now: https://lnkd.in/g8YR6T-R

Day 1 of the Bioprocess International Asia Main Conference has officially started! 🥳 Our exceptional chairperson, Daisuke Kajihara , opened the day by introducing our keynote speaker, Takashi Kaminagayoshi from Takeda : 💡 Advanced Biomanufacturing Facilities - A Case Study 💡 We've also heard from Jack Wong and Christiane Hartmann in this morning's first session! Throughout the day, we'll gain valuable insights from a lineup of experts including Niki Wong , Sanjay Nilapwar, Wei Huang, Minh Tran , Jonggu (Kevin) Kim , Changlin Dou, Christoph Herwig , Haruki Takeuchi, Yasuhiro Takagi , Zach Pang, 🌞 Thanks to our sponsors and exhibitors for supporting the event! #BPIAsia #CGT #kyoto #japan #biotech #biopharma Informa Connect Informa Connect Life Sciences BioProcess International

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BioProcess International