Foghorn Therapeutics Inc., a clinical-stage biopharmaceutical company, discovers and develops medicines targeting genetically determined dependencies within the chromatin regulatory system. The company uses its proprietary Gene Traffic Control platform to identify, validate, and potentially drug targets within the system. It is developing FHD-286, a small molecule inhibitor of the enzymatic activity of BRG1 and BRM for the treatment of metastatic uveal melanoma and relapsed and/or refractory acute myeloid leukemia and myelodysplastic syndrome; and FHD-609, a small molecule protein degrader for BRD9 to treat patients with synovial sarcoma. The company is also developing an enzymatic inhibitor and a protein degrader as selective modulators of BRM; and ARID1B selective modulators for the treatment of ovarian, endometrial, colorectal, bladder, and gastric cancers. It has a research collaboration and license agreement with Merck Sharp & Dohme Corp. to discover and develop novel oncology therapeutics against a transcription factor target; and with Loxo Oncology to create novel oncology medicines. Foghorn Therapeutics Inc. was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.

Foghorn Therapeutics Inc.

Foghorn Therapeutics is pioneering the discovery and development of a new class of medicines targeting genetically determined dependencies within the chromatin regulatory system, an untapped opportunity for therapeutic intervention. Our proprietary Gene Traffic Control® platform gives us an integrated, mechanistic understanding of how the various components of the chromatin regulatory system interact, allowing us to identify, validate and potentially drug targets within the system.

Flagship Pioneering

Casdin Capital

Invus

Irving Investors

Happy New Year from all of us at Foghorn! As we kick off 2024, we look forward to the year ahead as we continue to advance our mission to transform patient’s lives by correcting abnormal gene expression. #biotechnology #innovation #oncology

Check out photos of our Foghorn team, who had fun swapping surprises at our end of year holiday party. From all of us at Foghorn, wishing everyone a healthy and happy holiday season! #HappyHolidays

That's a wrap on the 65th Annual American Society of Hematology Meeting! Our team enjoyed coming together with the scientific community to present data and talk about our novel approach to modulating the chromatin regulatory system. Read all of our recent data presentations from #ASH23 and beyond: https://bit.ly/3GJ2vkZ

Martin (Murphy) Hentemann Kathleen Healy Caroline Almon #biotechnology #innovation #TPD

Meet Alexia Kalogeropulou, one of our brilliant scientists at Foghorn. Alexia shares why she loves the collaborative culture that enables us to advance our mission to transform the lives of people living with a wide spectrum of diseases. #LifeAtFoghorn #WomenInSTEM #biotechnology

Join us at the 2nd Annual TPD Assay Development & Screening Summit, where our Head of #DrugDiscovery, Marina Nelen, will be part of a panel to discuss high-throughput screening approaches and applications of assay techniques to degrader triage and profiling. See the agenda: https://ow.ly/J9Bh50QfwVc
#biotechnology #innovation #proteindegradation

We’re looking forward to the 65th American Society of Hematology Annual Meeting and Exposition, where clinical data from the Phase 1 dose-escalation study of FHD-286 in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) will be presented. Learn more: https://ow.ly/wc3q50Qel4h
#ASH23

We know that our people are the key to our success, which is why we embrace a people first culture. Our culture is just one reason that Madeleine Henley was drawn to Foghorn. Learn more about our culture: https://ow.ly/Ca4050Qe2u8 

#LifeAtFoghorn #WomenInSTEM

Happy #Thanksgiving to all! Today, we are especially thankful for the incredible Foghorn team and their unwavering commitment to our mission of transforming lives across a wide spectrum of diseases. #biotechnology #innovation

Last week, we had the pleasure of joining other leading experts in the chromatin and epigenetics field during #Epi2023, where Dave Lahr gave a presentation on our preclinical work during a session on the nucleosome and chromatin remodeling. Find all our recent data presentations here: https://lnkd.in/gUtu9Wfi

#biotechnology #oncology #innovation

Congratulations to this year's recipients of the 2023 Paul Marks Prize for Cancer Research, including our scientific co-founder, Cigall Kadoch! This award underscores the important work being done at Foghorn to address breakdowns in the chromatin regulatory targets to advance novel treatments in cancer and beyond. #oncology #cancerresearch #innovation

	Dec '18	Dec '19	Dec '20	Dec '21	Dec '22	Dec '23
revenue			430K -	1.32M 206.74%	19.23M 1,357.77%	34.16M 77.63%
cost of revenue					19.23K -	8.66M 44,943.69%
gross profit			430K -	1.32M 206.74%	19.21M 1,356.31%	25.49M 32.72%
selling and marketing expenses						-5.21M -
general and administrative expenses	4.82M -	6.72M 39.34%	11.25M 67.30%	21.73M 93.21%	30.75M 41.51%	32.37M 5.29%
selling general and administrative expenses	4.82M -	6.72M 39.34%	11.25M 67.30%	21.73M 93.21%	30.75M 41.51%	27.16M 11.66%
research and development expenses	21.23M -	44.36M 109.01%	57.72M 30.10%	80.33M 39.18%	105.62M 31.49%	106.24M 0.59%
other expenses					8.26M -	2.83M 65.71%
cost and expenses	26.05M -	51.08M 96.11%	68.96M 35.00%	102.05M 47.99%	136.37M 33.62%	142.06M 4.18%
operating expenses	26.05M -	51.08M 96.11%	68.96M 35.00%	102.05M 47.99%	136.37M 33.62%	133.40M 2.17%
interest expense	371K -	540K 45.55%	979K 81.30%	1.91M 94.69%	-11.57M 706.91%
ebitda	-25.56M -	-49.90M 95.23%	-66.20M 32.68%	-94.95M 43.43%	-117.14M 23.36%	-99.25M 15.27%
operating income	-26.05M -	-51.08M 96.11%	-68.53M 34.15%	-100.73M 46.99%	-117.14M 16.28%	-107.91M 7.88%
depreciation and amortization	379K -	1.19M 213.46%	2.33M 95.96%	5.78M 148.28%	3.32M 42.54%	8.66M 160.79%
total other income expenses net	-30K -	-44K 46.67%	-269K 511.36%	-586K 117.84%	8.26M 1,508.70%	13.71M 66.03%
income before tax	-26.34M -	-51.13M 94.13%	-68.80M 34.56%	-101.32M 47.27%	-108.88M 7.46%	-94.20M 13.48%
income tax expense	83K -	540K 550.60%	979K 81.30%	1.91M 94.69%	-8.26K 100.43%	4.23M 51,293.22%
net income	-26.34M -	-51.67M 96.18%	-69.78M 35.05%	-103.23M 47.93%	-108.87M 5.47%	-98.43M 9.60%
weighted average shs out	19.63M -	22.13M 12.73%	11.05M 50.08%	37.17M 236.49%	41.59M 11.89%	41.97M 0.92%
weighted average shs out dil	19.63M -	22.13M 12.73%	11.05M 50.08%	37.17M 236.49%	41.59M 11.89%	41.97M 0.92%
eps	-1.34 -	-2.34 74.63%	-6.32 170.09%	-2.78 56.01%	-2.62 5.76%	-2.34 10.69%
epsdiluted	-1.34 -	-2.34 74.63%	-6.32 170.09%	-2.78 56.01%	-2.62 5.76%	-2.34 10.69%

COM:FOGHORNTX

Foghorn Therapeutics Inc.

Last Close

7.86

21/11 21:00

Market Cap

265.58M

Beta: -

Volume Today

69.99K

Avg: -

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