Human Immunology Biosciences (HI-Bio™) is a clinical-stage biotechnology company developing precision therapies for patients with severe immune-mediated diseases (IMDs). The company aims to address the high unmet medical needs in autoimmune, allergic, and inflammatory diseases through targeted therapies that target the dysfunction of cells in the immune system. HI-Bio leverages human genetic and immunological insights to deliver novel treatments for IMDs.

Jeff He

Robert Nicol

Human Immunology Biosciences

Human Immunology Biosciences (HI-Bio) is leading clinical immunology into its next chapter with therapies that target cellular drivers of disease. HI-Bio uses a precision medicine approach to deliver therapies for patients with the auto-immune, allergic and inflammatory diseases that can together be referred to as immune-mediated diseases (IMDs).

ARCH Venture Partners

Jeito Capital

Monograph Capital

MorphoSys

Alpha Wave Global

Arkin Holdings

Viking Global Investors

HI-Bio

Last week, members of our team attended the American Society of Nephrology’s annual Kidney Week meeting. We were excited to present final data from the Phase 2 M-PLACE trial of felzartamab in patients with primary membranous nephropathy and engage and learn from other attendees and presenters.
 
Thank you to our collaborators, advisors and everyone who made the conference possible! Read more about the posters and presentations by our team: https://lnkd.in/eCTPMiEg

We are excited to announce that the U.S. Food and Drug Administration has granted Breakthrough Therapy designation for felzartamab for primary membranous nephropathy! 
 
This is a recognition of the promising data we have collected to date and is an important step forward in our work to develop targeted therapies to treat severe immune-mediated diseases. Learn more: https://lnkd.in/e-tfq6h9

Attending the American Society of Nephrology’s Kidney Week? We’re excited to share data on our clinically differentiated anti-CD38 candidate, felzartamab: posters on lupus nephritis study design and on mechanism of action, and an oral presentation with full Phase 2 safety and efficacy data in primary membranous nephropathy.
 
Check out the abstracts here: https://lnkd.in/ep-mzz-j #KidneyWk

We are excited to announce that we have initiated a second clinical-stage program, HIB210, an investigational monoclonal antibody targeting C5aR1. Targeting this receptor has the potential to transform the treatment of a variety of high burden immune-mediated diseases (IMDs) for patients in need.
 
Learn more about this exciting milestone: https://lnkd.in/gcwAjwJy

We are excited to announce that the U.S. Food and Drug Administration has granted orphan drug designation for felzartamab, our investigational agent that is in development for the treatment of primary membranous nephropathy!
 
This is an important step forward in our work to develop targeted therapies to treat rare, immune-mediated diseases. Learn more: https://lnkd.in/eGWyx4C3

Today is the second annual IgAN Awareness Day! IgAN is a rare, immune-mediated disease and we are grateful to investigators for their efforts to bring therapies to patients in need. Thanks to the IGAN Foundation for their work to raise awareness around the disease! #IgANAware

We are thrilled to announce the appointment of Uptal Patel, MD, as Chief Medical Officer! Uptal joins HI-Bio from AstraZeneca where he served as the Head of Clinical Renal and Executive Group Director in Early Cardiovascular, Renal and Metabolism (CVRM). We look forward to working with Uptal to accelerate our clinical programs in Primary Membranous Nephropathy and across the immune-mediated disease landscape.
 
We are also excited to welcome Sunil Agarwal, MD, to our Board of Directors. Sunil was most recently Executive Vice President, Head of Development and Chief Medical Officer at Sana Biotechnology. His deep experience in clinical development and with the drug approval process will invaluable as we advance our pipeline.
 
Learn more about Uptal and Sunil’s backgrounds and the value they bring to our team: https://lnkd.in/e2iKTKWr
 
#PrimaryMembranousNephropathy #immunemediateddisease

We are excited to share positive Phase 2 data from two studies of felzartamab for the treatment of Primary Membranous Nephropathy (PMN). The studies showed reduction in pathogenic antibody levels and proteinuria remissions that may signal renal recovery.
 
PMN is a rare immune-mediated disease (IMD) of the kidney that impacts more than 36,000 patients in the United States, and over 4,000 new patients every year. PMN imposes a high burden on patients and is one of the most common causes of nephrotic syndrome. There are currently no approved therapies for PMN.
 
We are focused on developing felzartamab in PMN and other IMDs to address patients’ significant unmet needs. Learn more about the studies: https://lnkd.in/eWVX7ZQE

#PrimaryMembranousNephropathy #felzartamab #immunemediateddisease

Few targeted therapies exist for immune-mediated disease (IMDs), including autoimmune diseases. As #AutoimmuneAwarenessMonth comes to a close, learn more about our lead program, felzartamab, and how we are targeting the cellular drivers of disease to develop precision therapies for patients in need. https://hibio.com

March is #NationalKidneyMonth and today is #WorldKidneyDay, dedicated to raising awareness around the importance of kidney health, especially rare, immune-mediated diseases like Membranous Nephropathy and IgA Nephropathy.
 
We are dedicated to developing targeted therapies to treat these diseases and more through our precision medicine approach. Through our commitment to achieve better results for patients affected by IMDs, we are leading clinical immunology into its next chapter.

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Company Name	Human Immunology Biosciences
Symbol
MSH ID	COM:HIBIO
Market	PRIVATE
Sector	Healthcare
Industry	Biotechnology
Country	US
Stage	Series D
Employee Count	47
Website	hibio.com
LinkedIn	hibio
Founders

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Monthly Web Traffic	878
Web Traffic Growth	1.49
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Raised Capital	75M

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COM:HIBIO

Human Immunology Biosciences

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