Lexeo Therapeutics, Inc. operates as a clinical-stage genetic medicine company that focuses on hereditary and acquired diseases. The company develops LX2006, which is an AAVrh10-based gene therapy candidate for the treatment of Friedreich's ataxia (FA) cardiomyopathy; LX2020, an AAVrh10-based gene therapy candidate for the treatment of arrhythmogenic cardiomyopathy; LX2021, a gene therapy candidate for the treatment of DSP cardiomyopathy associated with it; and LX2022, a gene therapy candidate for the treatment of HCM caused by TNNI3 mutations. It also develops LX1001, an AAVrh10-based gene therapy candidate for the treatment of APOE4 homozygous; LX1020, a gene therapy candidate for the treatment of APOE4 homozygous; LX1021 for the treatment of APOE4 homozygotes; and LX1004 for the treatment of CLN2 Batten disease. The company was incorporated in 2017 and is based in New York, New York.

Lexeo Therapeutics, Inc. Common Stock

Based in New York City, Lexeo Therapeutics is a clinical-stage genetic medicines company dedicated to transforming healthcare by applying pioneering science to fundamentally change how disease is treated.  Building on groundbreaking research from Weill Cornell Medicine and the University of California San Diego, Lexeo partners with preeminent institutions on the cutting edge of gene therapy research.  Using a stepwise development approach, Lexeo is leveraging early proof-of-concept functional and biomarker data to advance a pipeline of cardiovascular and APOE4 associated Alzheimer's disease programs, and is led by pioneers and experts with decades of collective experience in genetic medicines, rare disease drug development, manufacturing and commercialization. 

For more information, please visit www.lexeotx.com.

Sarepta Therapeutics

Woodline Partners

Alexandria Venture Investments

Omega Funds

PBM Capital Group

Invus

Alzheimer's Drug Discovery Foundation

Janus Henderson Investors

Longitude Capital

Lundbeckfonden Ventures

CAM Capital

Verition Fund Management

D1 Capital Partners

Eventide

Gray’s Creek Capital Partners

Intus Capital

Laurion Capital Management

Lexeo Therapeutics

Happy holidays to the team members, friends, family, partners, physicians and patients who have contributed to Lexeo’s work in 2023!

In 2023, Lexeo participated in numerous local events to join forces with patient advocates who are raising awareness about devastating diseases such as #Alzheimer’s, #FriedreichsAtaxia and #ArrhythmogenicCardiomyopathy.
 
Look back on some of our favorite photos from the year with Friedreich's Ataxia Research Alliance (FARA) and Alzheimer's Association®!

We are pleased to announce the FDA has granted Orphan Drug designation and Fast Track designation to LX2020, our #genetherapy candidate designed to treat arrhythmogenic cardiomyopathy caused by mutations in the PKP2 gene (PKP2-ACM).

Read the full press release here: https://lnkd.in/eq6wzhin

$LXEO shares began trading on Nasdaq last month.
 
Here's a peek behind the curtain of the biggest highlights from IPO day, ringing the Nasdaq closing bell and our event celebrating the Lexeo team for making this possible!
 
#LexeoListed

Yesterday, we reported our Q3 financial results and operational highlights. Check out the highlights below or read the full press release here: https://bit.ly/3Njy60f

	Dec '20	Dec '21	Dec '22	Dec '23
net income	-5.15M -	-50.62M 882.42%	-59.28M 17.10%	-66.39M 12.01%
depreciation and amortization		13K -	1.15M 8,707.69%	1.84M 60.96%
deferred income tax
stock based compensation		386K -	1.78M 361.40%	3.04M 70.86%
change in working capital	150.15K -	6.04M 3,923.26%	1.79M 70.35%	1.48M 17.25%
accounts receivables
inventory
accounts payables	44.32K -	3.02M 6,702.95%	-426K 114.13%	-180K 57.75%
other working capital	105.83K -	3.03M 2,759.22%	2.22M 26.73%	1.66M 25.03%
other non cash items	1.87M -			530K -
net cash provided by operating activities	-3.13M -	-44.18M 1,310.04%	-54.56M 23.49%	-59.50M 9.05%
investments in property plant and equipment		-188K -	-901K 379.26%	-165K 81.69%
acquisitions net
purchases of investments
sales maturities of investments
other investing activites
net cash used for investing activites		-188K -	-901K 379.26%	-165K 81.69%
debt repayment			-163K -	-425K 160.74%
common stock issued				100.25M -
common stock repurchased
dividends paid
other financing activites	32.38M -	150.86M 365.91%	352K 99.77%	3.96M 1,026.42%
net cash used provided by financing activities	32.38M -	150.86M 365.91%	189K 99.87%	103.79M 54,815.87%
effect of forex changes on cash
net change in cash	29.25M -	106.49M 264.12%	-55.27M 151.90%	44.13M 179.84%
cash at beginning of period	127.86K -	29.37M 22,872.78%	135.86M 362.53%	80.59M 40.68%
cash at end of period	29.37M -	135.86M 362.53%	80.59M 40.68%	124.72M 54.76%
operating cash flow	-3.13M -	-44.18M 1,310.04%	-54.56M 23.49%	-59.50M 9.05%
capital expenditure		-188K -	-901K 379.26%	-165K 81.69%
free cash flow	-3.13M -	-44.37M 1,316.04%	-55.46M 25.00%	-59.66M 7.57%

LXEO

COM:LEXEOTX

Lexeo

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21/11 21:00

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