NuVasive, Inc., a medical technology company, develops, manufactures, and sells procedural solutions for spine surgery. It provides surgical access instruments, including Maxcess integrated split-blade retractor system that enable less-invasive surgical techniques by minimizing soft tissue disruption during spine surgery; specialized spinal implants to advance spinal fusion by enhancing the osseointegration and biomechanical properties of implant materials, including porous titanium and porous polyetheretherketone; and fixation system that facilitates the preservation and restoration of patient alignment. The company also offers cervical total disc replacement technology for cervical spinal fusion surgery; neuromonitoring systems, which use proprietary software-driven nerve detection and avoidance technology, and its intraoperative neuromonitoring services and support; and Pulse platform, a software ecosystem that integrates multiple hardware technologies into a single, condensed footprint in the operating room. In addition, it provides expandable growing rod implant systems for the treatment of early-onset scoliosis; various biologics that are used to aid in the spinal fusion or bone healing process; Precice, an intramedullary implant device that utilizes the MAGEC technology to non-invasively lengthen the femur and tibia; and onsite and remote monitoring of the neurological systems of patients undergoing spinal and brain-related surgeries. The company sells its products to patients, surgeons, hospitals, and insurers through independent sales agents, directly employed sales personnel, and distributors in the United States and internationally. NuVasive, Inc. was incorporated in 1997 and is headquartered in San Diego, California.

NuVasive, Inc.

Cook Medical is involved in the development and manufacture of medical devices for minimally invasive procedures.

Cook Medical

Integra LifeSciences Holdings Corporation develops, manufactures, and markets surgical implants and medical instruments for use in neurosurgery, extremity reconstruction, and general surgery. It operates in two segments, Codman Specialty Surgical and Tissue Technologies. The company offers neurosurgery and neuro critical care products, including tissue ablation equipment, dural repair products, cerebral spinal fluid management devices, intracranial monitoring equipment, and cranial stabilization equipment; and surgical headlamps and instrumentation, as well as asset management software and support, and after-market services. It also sells approximately 40,000 instrument patterns, and surgical and lighting products to hospitals and surgery centers, as well as dental, podiatry, and veterinary offices. In addition, the company provides regenerative technology products for the treatment of acute and chronic wounds; and surgical tissue repair products for hernia repair, peripheral nerve repair and protection, and tendon repair. Further, it offers skin and wound repair, plastics and surgical reconstruction products, bone grafts, and nerve and tendon repair products. The company offers its products directly through various sales forces and other distribution channels to the hospitals, integrated health networks, group purchasing organizations, clinicians, surgery centers, and health care providers in the United States, Europe, Asia Pacific, and internationally. Integra LifeSciences Holdings Corporation was incorporated in 1989 and is headquartered in Princeton, New Jersey.

Integra LifeSciences Holdings Corporation

Orthofix Medical Inc. operates as a medical device and biologics company in the United States, Italy, Germany, France, the United Kingdom, Brazil, and internationally. It operates through two segments, Global Spine and Global Orthopedics. The Global Spine segment manufactures, distributes, and provides support services for bone growth stimulator devices that enhance bone fusion, as well as used as a therapeutic treatment for non-spinal and appendicular fractures. This segment also designs, develops, and markets a portfolio of motion preservation and fixation implant products, which are used in surgical procedures of the spine; and a portfolio of products and tissue forms that allow physicians to treat a range of spinal and orthopedic conditions, as well as markets regenerative non-tissue biologic solutions derived from synthetic materials. The Global Orthopedics segment designs, develops, and markets orthopedic products that are used in fracture repair, deformity correction, and bone reconstruction procedures. The company markets and distributes its products through direct sales representatives; independent distributors; and employed and independent sales representatives to physicians, hospitals, ambulatory surgery centers, integrated health delivery systems, and other purchasing organizations. The company was formerly known as Orthofix International N.V. and changed its name to Orthofix Medical Inc. in July 2018. Orthofix Medical Inc. was founded in 1980 and is headquartered in Lewisville, Texas.

Orthofix Medical Inc.

NuVasive specializes in developing and providing innovative solutions for minimally invasive spine surgery. The company offers a range of surgical solutions and services for spinal disorders.

Metric
Company Name	NuVasive, Inc.	Cook Medical	Integra LifeSciences Holdings Corporation	Orthofix Medical Inc.
Symbol	NUVA		IART	OFIX
MSH ID	COM:NUVASIVE	COM:COOKMEDICAL	COM:INTEGRALIFE	COM:ORTHOFIX
Market	STOCKS	PRIVATE	STOCKS	STOCKS
Sector	Healthcare	Healthcare & Health Services	Healthcare	Healthcare
Industry	Medical - Devices	Medical Devices	Medical - Devices	Medical - Devices
Country	US	US	US	US
Stage
Employee Count	3K		3.95K	1.63K
Website	nuvasive.com	cookmedical.com	integralife.com	orthofix.com
LinkedIn
Founders

Metric
Market Cap	2.08B		2.31B	560.31M
Enterprise Value
Monthly Web Traffic		92.53K
Web Traffic Growth		-0.06
Valuation
Raised Capital

Metric
Revenue	1.20B	1.54B	746.64M
Revenue (LTM)
Revenue (NTM)
Gross Profit	865.43M	888.39M	468.87M
EBITDA	211.80M	297.59M	-88.70M
Operating Income	64.77M	174.08M	-141.76M
Net Income	40.41M	67.74M	-151.40M
EPS	0.78	0.85	-4.12
Diluted EPS	0.76	0.84	-4.12
Revenue 2022
Revenue 2023
Revenue 2024
Revenue 2025
Revenue 2026

Metric
Revenue Growth (LTM)
Revenue Growth (NTM)
Gross Profit Growth (LTM)
EBITDA Growth (LTM)
Net Income Growth (LTM)
14-Day Growth Score
28-Day Growth Score
90-Day Growth Score
365-Day Growth Score

Metric
Gross Profit Margin	0.72	0.67	0.66
Operating Profit Margin	0.08	0.09	-0.12
EBITDA Margin	0.18	0.19	-0.12
Net Profit Margin	0.03	0.04	-0.16
Return on Equity	0.03	0.04	-0.21
Return on Assets	0.01	0.02	-0.14
Return on Capital Employed	0.05	0.04	-0.12

COM:NUVASIVE

NuVasive

Last Close

40.66

31/08 20:00

Market Cap

2.08B

Beta: -

Volume Today

30.59M

Avg: -

Company Overview

Market Metrics

Financial Performance

Growth Metrics

Profitability Ratios

Valuation Multiples

Operational Metrics

Cash Flow Metrics

Balance Sheet Metrics

Efficiency Metrics

Metric
P/E Ratio	73.24	32.01	-3.83
P/B Ratio	2.33	2.04	0.85
Revenue Multiple (LTM)
Revenue Multiple (NTM)
EBITDA Multiple (LTM)
EBITDA Multiple (NTM)
Price to Sales Ratio	2.24	1.74	0.86
EV Multiple	8.48	16.24	-3.69

Metric
Days Sales Outstanding	79.51	60.64	62.31
Days Payables Outstanding	124.79	53.84	84.66
Days Inventory Outstanding	480.24	293.69	306.42
Operating Cycle	584.96	351.22	369.04
Cash Conversion Cycle	422.32	282.50	288.55
Asset Turnover	0.59	0.41	0.87

Metric
Operating Cash Flow	169.12M	139.96M	-45.75M
Free Cash Flow	29.69M	73.09M	-107.80M
Cash Flow to Debt	0.15	0.63	-0.12
Operating Cash Flow/Sales	0.11	0.09	-0.02
Free Cash Flow Yield	-0.00	0.04	-0.17

Metric
Cash & Equivalents	248.66M	276.40M	37.76M
Accounts Receivable	-37.18M	4.59M	-10.41M
Inventory	338.60M	389.61M	222.17M
Goodwill	639.66M	1.06B	194.93M
Debt to Capitalization	0.50	0.55	0.20
Debt to Assets	0.43	0.28	0.10
Current Ratio	1.25	2.89	2.58
Quick Ratio	0.60	3.35	1.19

Metric
Rule of 40 (LTM)
Rule of 40 (NTM)
Stock Comp to Revenue	0.02	0.01	0.06
R&D to Revenue	0.08	0.07	0.11
SG&A to Revenue			0.20