Pairwise focuses on the application of CRISPR technology in food and agriculture, delivering unique varieties of crops for growers and consumers.

Tom Adams

Haven Baker

Pairwise

Caribou Biosciences, Inc., a clinical-stage biopharmaceutical company, engages in the development of genome-edited allogeneic cell therapies for the treatment of hematologic malignancies and solid tumors in the United States and internationally. Its lead product candidates are CB-010, an allogeneic anti-CD19 CAR-T cell therapy that is in phase 1 clinical trial to treat relapsed or refractory B cell non-Hodgkin lymphoma; and CB-011, an allogeneic anti-BCMA CAR-T cell therapy for the treatment of relapsed or refractory multiple myeloma. The company also develops CB-012, an allogeneic anti-CD371 CAR-T cell therapy for the treatment of relapsed or refractory acute myeloid leukemia; and CB-020, an allogeneic CAR-NK cell therapy for the treatment of solid tumors. It has collaboration with AbbVie Manufacturing Management Unlimited Company to develop CAR-T cell therapies. The company was incorporated in 2011 and is headquartered in Berkeley, California.

James Berger

Martin Jinek

Jennifer Doudna

Rachel E. Haurwitz

Caribou Biosciences, Inc.

Corteva, Inc. operates in the agriculture business. It operates through two segments, Seed and Crop Protection. The Seed segment develops and supplies advanced germplasm and traits that produce optimum yield for farms. It offers trait technologies that enhance resistance to weather, disease, insects, and herbicides used to control weeds, as well as food and nutritional characteristics. This segment also provides digital solutions that assist farmer decision-making with a view to optimize product selection, and maximize yield and profitability. The Crop Protection segment offers products that protect against weeds, insects and other pests, and diseases, as well as enhances crop health above and below ground through nitrogen management and seed-applied technologies. This segment provides herbicides, insecticides, nitrogen stabilizers, and pasture and range management herbicides. It serves agricultural input industry. The company operates in the United States, Canada, Latin America, the Asia Pacific, Europe, the Middle East, and Africa. Corteva, Inc. was incorporated in 2018 and is headquartered in Indianapolis, Indiana.

Corteva, Inc.

CRISPR Biotech Engineering is an early-stage genome editing company that is committed to using innovative CRISPR-Cas9 technology to improve human lives.

CRISPR Biotech Engineering

Pairwise  | 12,818 followers on LinkedIn. Building a healthier world through better fruits and vegetables | Pairwise is a start-up food company that uses technology to break down the barriers that keep us from eating produce. At Pairwise, we are passionate about building a healthier world through better fruits and vegetables.
 
Headquartered in Durham, NC, our team is made up of leaders in R&amp;D, agriculture, and consumer products.

Tom Spaulding

Vice President, Venture Investments at Leaps by Bayer

Derek Norman

Lead Translator at Arena BioWorks; Professor of Pathology (on leave 2023-2025) at Harvard Medical School

Keith Joung

Chief Operating Officer at Pairwise

Ian Miller

We are thrilled to share that we have developed the world's first seedless blackberry! “A key challenge in our food system is helping people eat more high-quality, healthy foods. As part of our drive to increase the consumption of fruit and vegetables, we’re working to provide consumers with new, highly nutritious food options with improved flavor and convenience,” said Tom Adams, Pairwise Co-Founder and CEO. “With a deep understanding of the plant genome, an accurate, efficient, and scalable process, and streamlined pathway to commercialization, we are not only creating new products with our proprietary CRISPR technology, we are creating a new era of innovation in agriculture.” In addition to achieving the first seedless trait in any caneberry, we’ve created thornless and compact traits in the same variety to deliver benefits for consumers, growers, and the environment all in one.

We were so thankful to have been able to welcome U.S. Representative Deborah Ross during her visit to Pairwise. While she was with us, she learned about all the amazing things we are doing with CRISPR technology and plants, in order to address the challenges facing farmers, consumers and the environment. An additional thank you to North Carolina Life Sciences Organization President Laura Gunter for assisting in coordinating, and to both Laura and Representative Ross for being such strong supporters of start-ups such as Pairwise here in RTP! #CRISPR #Pairwise #innovation #agriculture

Meet one of our amazing interns, Sina Jamalzadegan ! Sina just completed a successful 11-week internship in Data Science with Pairwise . During this time, Sina advanced the utilization of machine learning algorithms to improve the efficiency predictions for gene editing tools, which will help enhance the efficiency of Pairwise’s highly productive editing pipeline. We are grateful for Sina's contribution and wish him the best in his future endeavors!

As we kick off our new partnership with Corteva Agriscience , we were thrilled to host Chuck Magro , Sam Eathington , Reza Rasoulpour, Wendy Pline Srnic , and Robert Lockhart this week for tours of our R&D center and meetings with our scientific and business leaders. By accelerating innovation through our leading gene editing platform and important collaborations like this partnership with Corteva, we’re excited to tackle some of the biggest challenges in global agriculture together – faster and with bigger reach – to deliver benefits to consumers, farmers, and the environment. Learn more about our partnership here: https://lnkd.in/eK-YQuPF #keepgrowing #innovateboldly #pairwise #corteva #cortevacatalyst #geneediting #precisonbreeding #startup #agtech #agrifoodtech #agritech #agriculture #farming #agribusiness #innovation #technology #tech #foodtech #foodsecurity #sustainability #climatechange

We’re thrilled to share a new #partnership with the International Institute of Tropical Agriculture (IITA) to improve yam cultivation. By optimizing this important staple crop, we’re aiming to narrow the widespread nutritional deficit in Africa. Learn more here: https://lnkd.in/e2RSYBf4 #IITA #CGIAR #Pairwise #geneediting #precisonbreeding #startup #agtech #agrifoodtech #agritech #agriculture #farming #agribusiness #innovation #technology #tech #foodtech #foodsecurity #sustainability #staplecrop #yam #Africa #climatechange #nutrition

We're thrilled to see #geneediting take center stage in our feature with Corteva Agriscience in Forbes . Click through to learn how we're applying this cutting edge technology to create solutions for some of the world's most pressing concerns.

Today, Pairwise co-founder and CEO, Dr. Tom Adams , joined Dr. Peter Beetham of Cibus and Dr. Fan-Li Chou of the American Seed Trade Association for Foreign Policy ’s Food+ forum at the United Nations General Assembly. During the “Sowing Solutions: Innovations in Climate-Resilient Seeds” panel, moderated by Maggie Lake , panelists discussed building resilient, secure global food systems in the face of climate change, regional conflicts, and more – including how gene editing will play a critical role in tackling some of the biggest global challenges in agriculture. #UNGA #UNGA79 #foodsecurity #sustainability #climatechange #biotech #asta #climateweek #seedinnovation #pairwise #geneediting #precisonbreeding #startup #agtech #agrifoodtech #agritech #agriculture #farming #agribusiness #innovation #technology #tech #foodtech

We are extremely proud to share two significant updates today that are not only big steps forward for our company, but also for realizing the global promise of gene editing technology in agriculture: 1) We have formed a five-year joint venture with Corteva Agriscience to accelerate the delivery of advanced gene editing products and technology, and develop crops that are more resilient to extreme weather events and climate change. 2) In parallel to this new collaboration, we have closed a $40M Series C funding round. Investors including Deerfield Management, Aliment Capital, and Leaps by Bayer, are joined by new investor Corteva through its Corteva Catalyst platform. Investments from this funding round will be used to scale our innovative product pipeline, including seedless berries and pitless cherries, as well as advance our industry-leading Fulcrum™ Platform. “Gene editing is poised to revolutionize agriculture, enabling the cultivation of crops that are more adaptive to climate change, are more nutritious and convenient for consumers, and deliver greater economics for growers. Through our Fulcrum™ Platform, we’re proud to be at the helm of applying this transformative technology in agriculture and, alongside partners like Corteva, accelerate the realization of these benefits across global stakeholders.” - Tom Adams, Pairwise Co-Founder and CEO Read the two announcements in our newsroom here: https://hubs.li/Q02Q1L3R0 #keepgrowing #innovateboldly #pairwise #corteva #cortevacatalyst #geneediting #precisonbreeding #fundraise #startup #investment #agtech #agrifoodtech #agritech #agriculture #farming #agribusiness #innovation #technology #tech #foodtech #foodsecurity #sustainability #climatechange

We're honored to be one of this year's SVG Ventures | THRIVE Top50 AgTech & FoodTech companies. We believe in the revolutionary potential of #geneediting for agriculture and are excited to champion the benefits of this technology for consumers, growers, and the environment.

Metric
Company Name	Pairwise	Caribou Biosciences, Inc.	Corteva, Inc.	CRISPR Biotech Engineering
Symbol		CRBU	CTVA
MSH ID	COM:PAIRWISE	COM:CARIBOUBIO	COM:CORTEVA	COM:CRISPR-BTE
Market	PRIVATE	STOCKS	STOCKS	PRIVATE
Sector	Consumer Goods	Healthcare	Basic Materials	Healthcare & Health Services
Industry	Food & Agriculture	Biotechnology	Agricultural Inputs	Biotechnology
Country	US	US	US	GB
Stage			Post-IPO Debt
Employee Count	168	158	22.50K
Website	pairwise.com	cariboubio.com	corteva.com	crispr-bte.com
LinkedIn	pairwise-plants	caribou-biosciences
Founders

Metric
Market Cap	205M	153.54M	35.56B
Enterprise Value
Monthly Web Traffic	7.21K	6.55K	215.13K
Web Traffic Growth	0.63	0.38	0.07
Valuation
Raised Capital		125M	1.20B

Metric
Revenue	34.48M	17.23B
Revenue (LTM)
Revenue (NTM)
Gross Profit	30.95M	17.23B
EBITDA	-112.53M	941M
Operating Income	-116.06M	941M
Net Income	-102.07M	735M
EPS	-1.38	1.04
Diluted EPS	-1.38	1.03
Revenue 2022
Revenue 2023
Revenue 2024
Revenue 2025
Revenue 2026

Metric
Revenue Growth (LTM)
Revenue Growth (NTM)
Gross Profit Growth (LTM)
EBITDA Growth (LTM)
Net Income Growth (LTM)
14-Day Growth Score
28-Day Growth Score
90-Day Growth Score
365-Day Growth Score

Metric
Gross Profit Margin	0.86	0.42
Operating Profit Margin	-3.37	0.13
EBITDA Margin	-3.26	0.05
Net Profit Margin	-2.87	0.05
Return on Equity	-0.30	0.04
Return on Assets	-0.22	0.02
Return on Capital Employed	-0.28	0.07

COM:PAIRWISE

Pairwise

Company Overview

Market Metrics

Financial Performance

Growth Metrics

Profitability Ratios

Valuation Multiples

Operational Metrics

Cash Flow Metrics

Balance Sheet Metrics

Efficiency Metrics

Metric
P/E Ratio	-6.14	38.67
P/B Ratio	1.41	1.45
Revenue Multiple (LTM)
Revenue Multiple (NTM)
EBITDA Multiple (LTM)
EBITDA Multiple (NTM)
Price to Sales Ratio	13.61	2.43
EV Multiple	-1.24	13.87

Metric
Days Sales Outstanding	54.16	138.50
Days Payables Outstanding		133.39
Days Inventory Outstanding		253.84
Operating Cycle	40.85	401.94
Cash Conversion Cycle	-139.62	267.85
Asset Turnover	0.09	0.41

Metric
Operating Cash Flow	-93.29M	1.77B
Free Cash Flow	-104.90M	1.17B
Cash Flow to Debt	-3.39	0.71
Operating Cash Flow/Sales	-2.71	0.15
Free Cash Flow Yield	-0.18	-0.00

Metric
Cash & Equivalents	51.16M	2.64B
Accounts Receivable	805K	358M
Inventory		6.90B
Goodwill		10.61B
Debt to Capitalization	0.08	0.16
Debt to Assets	0.06	0.14
Current Ratio	14.27	1.58
Quick Ratio	11.75	1.17

Metric
Rule of 40 (LTM)
Rule of 40 (NTM)
Stock Comp to Revenue	0.38	0.00
R&D to Revenue	3.08	0.08
SG&A to Revenue	1.08	0.04