Pixelgen Technologies develops technologies for enhanced cell surface protein phenotyping and colocalization analysis.

Pixelgen Technologies

Pixelgen Technologies AB was founded in 2020 by a team of passionate, experienced innovators and entrepreneurs with a vision to bring a new spatial understanding to biology by developing tools to facilitate the mapping of cell surface proteins and their spatial inter-relationships. 

Life operates by the spatial orchestration of proteins and at Pixelgen we have developed Molecular Pixelation that analyses cell surface proteins in a completely new way. Using current technologies, there are limitations of light and taking images influencing how many proteins and how many samples that can be analysed concurrently. With molecular pixelation you can measure hundreds of proteins simultaneously and obtain the spatial mapping of these proteins on the cell surface. 

This will be valuable for the understanding of life by gaining insights into cellular activity, by better understanding what constitutes the difference between health and disease.

Pixelgen is headquartered in Stockholm, Sweden.

Navigare Ventures

Colibri Ventures

Fibonacci Growth Capital

Industrifonden

We are excited to announce Pixelgen Technologies in-person seminar happening in Oslo in collaboration with Gregor Gilfillan, NorSeq Sequencing core (Ullevål) & Genomic Technology Group on September 17th, 2024.  It is an excellent opportunity to understand our technology from our FAS Louise Leijonancker and different applications of the technology from our Immunology Application Scientist Hanna van Ooijen. 

We are also happy to share that our valued customer María A. Globisch, PhD will have a presentation titled "Mapping the ex vivo effect of fludarabine in single cells using Molecular Pixelation".

👆 Register here: https://lnkd.in/dazD-N4c

Share it with your connections in Norway and register in advance. 

#oslo #spatialproteomics #immunology #CarTcell #AML #Leukemia #Molecularpixelation #PixelgenTechnologies #seminar #meetandgreet

We are thrilled to share the stylish results from our most recent #B2B client, Pixelgen Technologies, an impressive leader in biotechnology research, as we furnished their new office spaces at Forskaren 🔎

Pixelgen’s COO, Henrik Everberg, shared his thoughts on the project:
"We connected with Sweef while planning our move to our new premises in Forskaren. Sweef’s furniture and interior details perfectly align with our profile. Together with the Sweef staff, we quickly found a match to our company’s identity and created a beautiful work environment. The feedback from our employees and visitors has been overwhelmingly positive, and we’ve received many compliments on the fabrics, shapes, and comfort of our new furniture. It’s uplifting and inspiring to come to work when greeted by the warm and beautiful furniture and lighting in our lovely premises." 

Our mission is to create your #dreamoffice through:
🛋️ Personal consultation and tailored furniture solutions
🛋️ Visualization with 3D floor plans
🛋️ Flexible delivery and payment options

#interiordesign #office #sweef #ecommerce

Pixelgen Technologies, located at Forskaren in #Hagastaden, is at the forefront of innovative life science research tools. Follow our guest instagrammare Prajakta Sathe this week and learn about their Molecular Pixelation technology.
Stockholm Science City spreads information about the life science ecosystem, including through guest hosts on Instagram. New guests every week! Does your organization want to be one of our hosts? A few weeks are still unbooked during the autumn. Contact info@ssci.se!

#lifescience

Meet us at the European Symposium of Single Cell Proteomics in Vienna on 27th &28th August 2024. 
Michele Simonetti, Ph.D. will be presenting "Molecular Pixelation: Spatial Proteomics of single cells by next-generation sequencing" on 27th August 2024 from 14:00 to 14:35.

#ESCP2024 #Spatialproteomics #proteomics #conferencealert #proteins #spatialbiology #immunecells #proteins

#MPXMonday We are excited to announce the launch of our updated software website and a new version of pixelator software. 💻 

A crucial part of Molecular Pixelation (MPX) technology is the availability of its open-source software pixelator for analyzing the data generated after performing MPX. 👨💻 

Our new software website promises new tutorials, a blog, and more data sets to explore. 

Here is the link to our new software website: 
🖇https://lnkd.in/dEj_sDzp

Link to new tutorials, 
🖇 For R: https://lnkd.in/dRJ2jGxB

🖇 For Python: https://lnkd.in/dYZK8mEe

More information about the Pixelator 0.18 series can be found on this blog:
https://lnkd.in/d7Sq3Tdj

#MPXdataanalysis #MolecularPixelation #dataanalysis #newsoftware #Pixelator #newsoftwarewebsite #R #Python #MPXanalysis
#Spatialmetrics #spatialbiology #flowcytometry #proteins #cellsurface #PBMCs #CARTcell #Tcell #Bcell #immunology #spatialproteomics

Have you ever wondered about the opportunity to join the outstanding software team at Pixelgen Technologies? Please take a look at the two available positions, apply, or share them with your colleagues.

https://lnkd.in/dn8zBkVD

https://lnkd.in/dQ9mzqmV

#careerdevelopment #softwareengineer #biotech #molecularpixelation #immunology #pixelgentechnologies

Many of our customers find both these spatial metrics useful for their research. Please take a moment to answer the poll and share your favorite with us.
👉 The polarity score of a protein will tell you if the spatial distribution of that protein is non-random. The more polarized a marker is in a cell, the higher the polarity score.

👉 The colocalization score of two markers will tell you if the two markers appear at the same locations more often than expected by random chance, as well as how colocalized they are. The more colocalized two markers are in a cell, the higher the colocalization score. The colocalization can also be used to build colocalization networks, to look at protein groups.

More about the MPX v2 kit here: https://lnkd.in/dciE7g8A

More about Polarity Score and Colocalization here: https://lnkd.in/dpZ74pcG

#spatialbiology #spatialmetrics #cellsurface #cellsurfaceproteins #immunecells #PBMCs #lipidrafts #MolecularPixelation #MPXv2ishere

#MPXMonday Are you wondering if two proteins are colocalized or segregated on the immune cell surface of your cells? If so, Pixelgen Technologies's Molecular Pixelation MPX v2 kit might be able to help you solve the problem.

MPXv2 with optimized chemistry launched last month provides superior sensitivity for measurement of protein abundance and localization for all panel proteins in thousands of single cells. 

👉 The figure below illustrates the comparison of average pairwise colocalization scores for 32 proteins expressed in PHA-activated CD4+ T cells, generated using either MPX v1 or v2.

👉 MPX v2 showed a greater range of colocalization scores, both for positive scores - indicating colocalization of two proteins and negative scores - indicating segregation of two proteins.

More info: https://lnkd.in/dTs6CMgJ

#molecularpixelation #protein #colocalization #proteinabundance #multiprotein #spatialbiology #localization #proteome #cellsurface #immunecells #Tcells #MPXv2ishere #sensitivity #PHAactivated

Have you checked out the proteins in our Immunology Panel 2? Our panel includes immune markers for all major PBMC subsets and facilitates the detection of protein interaction complexes from the cell surface. We have 84 targets in the new panel. MPX workflow helps not only in determining the abundance of these proteins on the cell surface but also provides spatial information such as polarity score and colocalization score.

Which is your favorite immune cell marker?

#immunemarkers #immunecells #PBMCs #flowcytometry #immunologypanel #Tcells #Bcells #CDmarkers #antibodyvalidation #spatialbiology #spatialinformation

#MPXMonday We launched our new upgraded MPX v2 kit last month and here is a reminder if you have missed it during your holidays.

#MPXv2ishere #spatialbiology #proteomics #spatialproteomics #singlecell #celldynamics #cellactivity #cellsurface #immunecells #immunologypanel2 #pixelator

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