Protembis is a company that develops and delivers class III medical devices to improve patients' lives. Their team of experienced professionals brings innovative ideas from concept to clinical use.

Protembis GmbH

Protembis

Protembis is an Aachen, Germany based medical device startup. It develops a novel catheter-based filter device for use during cardiac interventions. The device is designed to minimize the risk of stroke and other neurological injury during these interventions – particularly during transcatheter aortic valve replacement procedures (TAVR/ TAVI).

The filter blocks embolic debris from entering the blood vessels leading to the brain. The initial safety and feasibility of the ProtEmbo® device has been demonstrated in a first-in-human study in 2017/ 2018. The imaging data of the study suggests that the ProtEmbo® device decreases the risk of brain injury by up to 90%.

Protembis has closed an oversubscribed $10M Series A financing round in 2018 and expects to bring its product to market maturity with this round. Therefore the team plans to conduct further clinical studies in heart centers in Europe and the U.S.

The ProtEmbo® device is not yet commercially available.

IFB Innovationsstarter

coparion

TechVision Fund

Abiomed

Congratulations to the authors of this final study report Simone Fezzi Darren Mylotte Dariusz Jagielak Nikos Werner. Use of the ProtEmbo cerebral embolic protection system was very safe, and shown to significantly reduce clinically meaningful cerebral lesions that could lead to stroke after TAVR.  ProtEmbo is the only CEP deployed via the left radial artery, and was intuitive to use in the 10 sites by 14 different operators, it was deployed on average in ~4 minutes.

https://lnkd.in/gNKF3TFt 

#Protembis #ProtEmbo #TAVR #Cerebralprotection #TAVI #innovationinhealth 

We are hiring a talented manufacturing engineer.

Protembis is an Aachen-based company dedicated to research, design and manufacturing of medical devices in the field of interventional cardiology. Founded in 2013 by Karl von Mangoldt  and Conrad Rasmus, Protembis is a steadily growing company in the medical industry preparing for commercialisation. 
 
To ensure extraordinary outcomes during this journey, we seek a highly motivated individual to join our Research and Development (R&D) group as a manufacturing engineer.
 
As a manufacturing engineer you will provide day to day support to production to ensure consistent, reliable and cost-effective manufacturing of the ProtEmbo System by studying product requirements, researching manufacturing, and testing methods.
 
 
Key Responsibilities:
 
· Investigate, recommend, and implement reliable, consistent, and efficient product assembly processes in coordination with Document Control and Quality System requirements.
· Conduct and lead activities related to process verification, validation and process risk assessments.
· Maintain contact with customers and suppliers to ensure quality standards for machinery and products are being met.
· Provide manufacturing decision-making information by calculating production, labour, and material costs.
 
Profile:
 
· You are characterized by a high sense of quality and responsibility, with attention to detail
· You have excellent problem-solving skills with the ability to lead and work independently
· You have the ability to work in a cross-functional team, demonstrating flexibility and resilience as well as a friendly nature.
· You have strong analytical and critical thinking skills
· Experience with clean-room manufacturing is desirable
 
Offer: 
 
· A challenging and diversified position within a high-potential, fast-growing, innovative medical device company.
· To work in a dynamic, respectful, and professional environment.
· A continuous learning environment.
· A full-time position
 
Interested?
Please send your CV together with an adapted cover letter/email to Protembis at info@protembis.com. Ref: Manufacturing Engineer. 
Your application and related information will remain strictly confidential.
#Protembis #manufacturingengineering #medicaldevices #wearehiringnow 

We are hiring an Operations Manager

Protembis is an Aachen-based company dedicated to research, design, and manufacturing of medical devices in the field of interventional cardiology. Founded in 2013 by Karl von Mangoldt and Conrad Rasmus, Protembis is a steadily growing company in the medical industry preparing for commercialisation. 
 
We are looking for a highly motivated Operations Manager to join our growing team to help support the commercialisation of the next generation of cerebral embolic protection systems.
 
This position is responsible for the management of supply chain operations, including planning, direction, coordination, and team leadership for purchasing, receiving, inspection, production, and sterilization of goods needed to maintain or produce the ProtEmbo System.
 
Key Responsibilities: 
 
· Demand Planning: Consult cross functional teams to determine the necessary information for demand planning purposes.
· Strategic Planning: Develop and implement supply chain strategies that align with the overall organizational goals and objectives. Identify opportunities for process improvements, cost savings, and operational efficiency enhancements. 
· Stock and Procurement Management: Ensuring that goods received are handled according to defined procedures and in a timely manner. 
· Management of Production: Work in close contact with production to ensure that every information and all materials are available at point of usage.
· Supplier Management and Implementation: First point of contact for suppliers providing goods related to clinical and commercial System. Lead the implementation of identified second sources together with R&D.
· Cost Optimization: Drive cost savings initiatives throughout the supply chain by analyzing data, identifying areas for improvement, and implementing effective strategies. Continuously monitor and optimize procurement processes to minimize costs while maintaining quality standards.

Profile:
 
· Minimum of a Bachelor’s or equivalent University Degree required; focused degree in Supply Chain, Logistics Sciences, Engineering, or related field is preferred 
· 5+ years of progressive experience in materials or other related supply chain or manufacturing operations role
· Expert language skills in German and English.
· You have the ability to take proactive approach to overcome challenges and achieve results Strong analytical and mathematics knowledge, demonstrated in operations experience.
 
Offer: 
 
· A challenging and diversified position within a high-potential, fast-growing, innovative medical device company.
· To work in a dynamic, respectful, and professional environment.
· A continuous learning environment.
· Full-time  position
 
Interested?
Please send your CV together with an adapted cover letter/email to Protembis at info@protembis.com. Ref: Operation Manager. 
Your application and related information will remain strictly confidential.


Protembis is a European medical device company focusing on clinical research of our product, the ProtEmbo® Cerebral Protection System, with the goal to protect the brain during Transcatheter Aortic Valve Replacement (TAVR), thereby minimizing cerebral lesions, improving patient quality of life, and reducing overall healthcare costs associated with TAVR procedures.
 
Protembis is progressing well with compelling data on safety and performance coming from a European trial in TAVR. We have approval from the FDA to initiate an Investigational Device Exemption (IDE) study in early 2024. 
 
To prepare for market access, we are recruiting a Head of Reimbursement and Market Access.
 
 
Key Responsibilities:
 
1.     Develop market access strategies in key global geographies to establish structural reimbursement for ProtEmbo. With specific focus on the USA and detailed process for Western Europe and recommendations for Japan.
2.     Collaborate with Health Economic Outcome Research (HEOR) specialists, the clinical KOL community, and groups such as the EuHTA agency to create materials to enable health technology assessment programs.
3.     Own the development of appropriate cost effectiveness models and/ or budget impact models.
4.     Collaborate with the commercial leadership on pricing models in key geographies, including US and Western Europe and ultimately Japan.
5.     Personal management of the execution on the market access strategy with priorities identified in US, Western Europe, Japan.
 
Profile:
 
·       Previous cardiovascular expertise in reimbursement, pricing, and health economics is a must, with minimum 5 years experience.
·       Experience of the USA Medicare coding, coverage, and payment systems for new technologies.
·       Hands on approach.
·       An industry experience of the TAVR market is an advantage.
·       A passion to work in a start-up environment and bring novel technologies to the market.
·       Can be based in USA or Western Europe.
 
Offer:
 
·       A challenging and diversified position within a high-potential, fast-growing, innovative medical device company.
·       To work in a dynamic, respectful, and professional environment.
·       International exposure, with learning and development opportunities.
·       An attractive compensation package in line with the position’s responsibilities and your experience.
 
Interested?
Please send your CV together with an adapted cover letter/ email to Protembis at info@protembis.com. Ref: Reimbursement.
Your application and related information will remain strictly confidential.
 
 

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