Puzzle Medical Devices is a Canadian company that develops a minimally invasive long-term hemodynamic transcatheter pump.

Puzzle Medical Devices

A Canadian based medical device company building world's first minimally invasive heart pump for patients with advanced heart failure.

AQC Capital

Anges Quebec

asterX

Boreal Ventures

Cathexis Ventures

Broadview Ventures

Cordis-X

Desjardins Capital

Bdc Thrive venture

BDC Venture Capital

Longview Ventures

Puzzle Medical Devices Inc.

Puzzle Medical Devices Inc. is delighted to announce the closing of its CAN$34 million Series A funding round to complete human feasibility study led by Cordis-X, a cardiovascular-focused investment vehicle backed by Ajax Health, Hellman & Friedman, and KKR. The round also included participation from Longview Ventures, Desjardins Capital, and BDC Capital’s Thrive Venture Fund, as well as existing investors.

Full press release: https://lnkd.in/eMVVQScF

"We are thrilled to have closed our Series A funding round and to have the support of such a renowned syndicate of investors," said Jade Doucet-Martineau, B. Eng., co-founder and CEO of Puzzle Medical Devices. "This milestone achievement is a reflection of the team's dedication and execution capability and will allow us to continue to execute on our mission of transforming the treatment of advanced heart failure."

Duke Rohlen, Executive Chairman of Cordis and CEO of Cordis-X and Ajax Health, commented, "What the Puzzle team has accomplished in a few short years is remarkable.  They’ve developed a truly novel solution to one of the most serious and difficult challenges in cardiovascular care. We are thrilled to partner with Puzzle to bring their exciting technology to a large population of heart failure patients who desperately need it."

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Thank you to all our partners, investors and advisors for being part of this incredible journey. Together, let's continue to strive towards our north star: improving heart failure patients' quality of life.

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Co-Founder & CTO

Francois Trudeau

Co-Founder

Gabriel Georges

Co-Founder and CEO

Jade Doucet-Martineau

Director, Regulatory Affairs

Marc-Andre Cote

Risk, Safety, Compliance

Maxime Rochon

Team Lead, Electrical Engineering

Xavier Beaulé

Engineering

Alexandru Marin

Patent Analyst

Dany Fillion

Consultant

Marc-Antoine Doyon

R&D Engineering

Philippe Cormier

David Prim

Daniel Gottlieb

Pascal Labrecque

Philippe Genereux, MD (Founding Advisor)

Maria Berkman

Aftab Kherani

Duke Rohlen

Cofounder and CEO

Gabriel Georges, MD

Cofounder and CSO

François Trudeau

Cofounder and CTO

Health Care Companies With Less Than $500M in Revenue (Top 10K)

Health Care Companies With Fewer Than 1000 Employees (Top 10K)

Health Care Companies With More Than 10 Employees (Top 10K)

Health Care Companies With Less Than $1B in Revenue (Top 10K)

Puzzle Medical is developing the ModulHeart, a modular percutaneous heart pump designed to reduce cardiac afterload and improve renal perfusion in patients with advanced heart failure who are not candidates for heart transplant or surgical mechanical circulatory support. The device’s modular design allows for hemodynamic support through multiple pumps anchored in parallel in the descending aorta. The design is expected to increase accessibility by enabling safe percutaneous implantation to support both renal and cardiac function, with low risk of bleeding, stroke, and pump thrombosis, while providing sustained symptom relief, reduced re-hospitalizations and improved overall quality of life. To date, Puzzle Medical has successfully:

○  	completed its first-in-human study with all patients experiencing improvements in cardiac and kidney function (2022); 
○  	completed a Seed financing round (2021); 
○  	built a strong Key Opinion Leaders committee (2021); 
○     received U.S. Food and Drug Administration (FDA) Breakthrough Device Designation (2021).

Series A - Puzzle Medical Devices

Seed Round - Puzzle Medical Devices

Centech

Non Equity Assistance - Puzzle Medical Devices

Montréal

Quebec

Canada

North America

Percutaneous assembly and methods of using same

Mammalian body conduit intralumenal device and lumen wall anchor assembly, …

Intraluminal modular powered medical system

Puzzle Medical Devices Inc. Announces the Successful Completion of its First-in-Human Study with its ModulHeart Breakthrough Percutaneous Heart Pump

System and method for assisting flow of a fluid in a vascular system of a …

Mammalian body implantable fluid flow influencing device

Puzzle Medical Devices Inc. announces the closing of its major Seed financing round to support its first-in-human study

Puzzle Medical Devices Inc. Receives U.S. Food and Drug Administration (FDA) Breakthrough Device Designation for Its Revolutionary Minimally Invasive Transcatheter Heart Pump

A modular percutaneous heart pump designed to support cardiac and renal function in patients with advanced heart failure, providing hemodynamic support through multiple pumps anchored in parallel in the descending aorta.

A small, lightweight controller designed to maximize patient mobility with a long-life battery for autonomous operation.

A comprehensive interface for programming and monitoring the function of ModulHeart during the cath lab procedure onsite.

United Kingdom

Europe

Israel

Asia

Greece

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Puzzle Medical Devices