SOTIO Biotech is developing potent immunotherapies for patients with cancer, focusing on advancing safer and more effective treatments through clinical development.

SOTIO Biotech

SOTIO Biotech | 8,879 followers on LinkedIn. Shaping the future of cancer immunotherapies by translating compelling science into patient benefit. | SOTIO Biotech is shaping the future of cancer immunotherapies by translating compelling science into patient benefit. SOTIO’s robust clinical pipeline includes a next-generation PD-1-inhibiting cytokine, a proprietary technology designed to improve on the efficacy of CAR T therapies and a new generation of potent and stable antibody-drug conjugates (ADCs). SOTIO is a member of the PPF Group.

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We will present at the American Association for Cancer Research conference on Tumor-body interactions: The Roles of Micro- and Macroenvironment in Cancer in Boston, MA. Šárka Vošahlíková ’s poster will focus on the role of PARP inhibitors for successful immunotherapy in #ovariancancer . #Biotechnology #CancerResearch #jsmePPF

This week, we will attend the Connective Tissue Oncology Society 2024 annual meeting in San Diego. Our Chief Executive Officer, Radek Spisek , Ph.D., and Senior Medical Director, Vivi Boura, MD, PhD , will connect with fellow sarcoma experts and discuss our ongoing efforts in advancing treatments for #sarcoma , such as through our DUET-01 clinical trial studying BOXR1030. #Biotechnology #CancerResearch #jsmePPF

Klára Plačková , junior scientist, is presenting at the INTERNATIONAL PAPILLOMAVIRUS SOCIETY - IPVS Conference in Edinburgh, UK, sharing insights on how tissue structure influences the pattern and density of immune cells that infiltrate tumors in HPV-related cancers. #Biotechnology #CancerResearch #IPVC2024 #jsmePPF

We are presenting a preclinical update on SOT201, a next-generation PD-1-targeting immunocytokine, this week at #SITC24 . New data support SOT201’s ability to reinvigorate exhausted immune cells in PD-1 sensitive and resistant tumor models. SOTIO’s two other posters at Society for Immunotherapy of Cancer (SITC) Annual Meeting provide an overview of the ongoing Ph1 clinical trial of SOT201 (VICTORIA-01) and explore the use of a chimeric PGC-1α transgene to enhance CAR T cell activity. Read more in our press release: https://bit.ly/3As1deT #Biotechnology #cancer #CancerResearch #SITC2024 #jsmePPF

#DidYouKnow that #PancreaticCancer is one of the deadliest cancers, with a 5-year survival rate of just 12%? Our Phase 1/2 CLAUDIO-01 trial is currently evaluating SOT102, a Claudin 18.2 ADC, for the treatment of pancreatic cancer. At SOTIO, we’re committed to changing the landscape of #cancer treatment by advancing innovative therapies that aim to improve the lives of patients battling devastating illnesses like pancreatic cancer. Learn more about SOT102 candidate at: https://bit.ly/48CzAfS #PancreaticCancerAwareness #PCAM #Biotechnology #CancerResearch #jsmePPF

Lung cancer is the most common #cancer in men and the second most common in women. As we observe #LungCancerAwarenessMonth , we reaffirm our dedication to advancing therapies for patients facing this significant unmet medical need. #Biotechnology #CancerResearch #jsmePPF

Next month we will be at the World ADC Event Series conference in San Diego. Martin Steegmaier , Chief Scientific Officer, will present on some of the latest progress in our portfolio of #ADC candidates for solid tumors. If you’re attending, be sure to stop by his presentation, or reach out to connect. #WorldADC #Biotechnology #CancerResearch #jsmePPF

Today we had the pleasure of welcoming the new Swiss ambassador, H.E. Urs Bucher, and his embassy colleagues to SOTIO Biotech ’s Prague office. Radek Spisek , Pavel Solsky and I gave our guests a tour of our lab space and presented the latest on SOTIO’s efforts to advance #cancer #research . Together with Luděk Sojka Sojka from our affiliate company SCTbio , we also visited lab space that is focused on the manufacturing of #celltherapies . SOTIO is one of the leaders in creating and promoting Czech-Swiss relations. Thank you for your visit and engaging in interesting discussion, Your Excellency! #cancerresearch #Switzerland #jsmePPF

Richard Kapsa

SOTIO will present three posters at the Society for Immunotherapy of Cancer (SITC) Meeting next month in Houston, Texas, including data supporting SOT201, a next-generation PD-1 targeting immunocytokine. Learn more details in our press release: https://bit.ly/48eWZU8 #SITC2024 #Biotechnology #DrugDevelopment #CancerResearch #jsmePPF

Our CEO, Radek Spisek , recently joined the Labiotech.eu #BeyondBiotechpodcast to discuss the pioneering developments in bispecific antibody-drug conjugates (ADCs) and their potential to revolutionize the field of #oncology . On bispecific ADCs, Radek shares: “There are good scientific reasons to believe that there are clinical situations or tumors that make sense to target [two antigens] at the same time, rather than to just go after one.” Tune in to learn more about SOTIO’s ADC platform, including SOT102, now in Phase 1/2 clinical studies in the U.S. and Europe: https://bit.ly/4eLwp7I #ADC #biotechnology #jsmePPF

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Chief Executive Officer

Geoffrey Hodge

President and Chief Operating Officer

Matthew Plaud

Vice President Information Technology

Dana Tomaszewski

Vice President, Technical Operations

Philip Levesque

Vice President of Discovery Research

Amy Smith

Group HR Director

Gordana Zafranovic

Sr. Director Clinical Operations

Janine McDermott

Regulatory Affairs and Quality Assurance, Vice President

Lorraine Whittemore

Director Clinical Project Management

Marek Hraska

Associate Director

Rachel Yao

Robyn Hunter

Chief Financial Officer

Chief Business Officer

Richard Sachse

Chief Medical Officer

Radek Spisek

Chief Executive Officer and Founder

Czech Republic Companies With Less Than $500M in Revenue

Biotechnology Companies With More Than 10 Employees (Top 10K)

Czech Republic Companies With More Than $10M in Revenue

European Union (EU) Companies With More Than $10M in Revenue (Top 10K)

Sotio is an international biotechnology company leading the efforts of PPF Group to build a diverse biotechnology portfolio through its own research & development, collaborations, in-licensing, investments, mergers, and acquisitions. The company is developing new medical therapies, focusing on the treatment of cancer and autoimmune diseases. The most advanced project is the SOTIO proprietary platform of active cellular immunotherapy (ACI) based on dendritic cells.

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Sotio

Sotio, Biocytogen link up in $325M ADC discovery pact

SOTIO Enters into Multi-Target Antibody Agreement with Biocytogen to Expand ADC Pipeline

SOTIO Presents Data on SOT201 Immunocytokine and Other Programs at SITC Annual Meeting

SOTIO Further Expands Next-Generation ADC Platform with License to Synaffix’s ADC Technology

Sotio enters license and option agreement with Synaffix to develop ADCs for solid tumors

Synaffix partners with SOTIO Biotech in deal worth up to $740m

SOTIO Provides Update on Interim Data from Clinical Trials of Nanrilkefusp Alfa

SOTIO Doses First Patient in AURELIO-05 Phase 2 Trial of Nanrilkefusp Alfa in Combination with Cetuximab

SOTIO exercises option on ADC program

Sotio exercises option for ADC SOT-106 under Legochem collaboration

A platform that develops stable and potent antibody-drug conjugates for targeted cancer treatment.

A platform designed to enhance T cell functionality in solid tumors by using novel transgenes.

A platform that activates immune cells in the tumor microenvironment through targeted cytokine delivery.

A technology that uses IL-15 to expand T and NK cells, enhancing anti-cancer immune responses.

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SOTIO Biotech develops immunotherapies for cancer treatment, focusing on advancing safer and effective options through clinical development. The company self-describes as focusing on a broad pipeline addressing various solid tumor types.

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