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Are T cells malignant?🧪

The FDA recently communicated they were investigating the potential risks of malignancies subsequent to CAR-T cell therapies.🚨

At a time when CAR-T cell therapies’ potential is being explored beyond cancer care, this news could entail great change in oncology, but also in other fields. 🥼

The stakes are high! Read more in our latest article.⬇️

https://lnkd.in/dguVaF5u

#tcells  #CARTTherapy #Immunotherapy #Cancer #CancerResearch #Oncology 

Weekly Recap of the Hottest M&A and Partnerships in the Biotech World! 🔥🤝

Merger and acquisition: 🔀
🇩🇪 Boehringer Ingelheim acquires 🇨🇭 T3 Pharmaceuticals AG | T3 Pharma eligible to receive up to 450 million CHF ($513 million) | Lead asset: genetically engineered bacteria targeting solid tumors

🇬🇧 Syncona Limited to acquire 🇬🇧 Freeline | Freeline to receive $28.3 million plus up to $15 million in secured convertible debt financing | Lead asset: AAV gene therapy for Gaucher disease type 1

Partnering: 🤝
🇺🇸 Avidity Biosciences, Inc. collaborates with 🇺🇸 Bristol Myers Squibb to develop and commercialize cardiovascular targets | Avidity to receive $100 million upfront and is eligible to receive up to $1.35 billion in R&D milestone payments, up to approximately $825 million in commercial milestone payments, plus tiered royalties

🇺🇸 AnaptysBio collaborates with 🇺🇸 🇬🇧 Centessa Pharmaceuticals to expand immune cell modulator pipeline, with Anaptys acquiring Centessa’s blood dendritic cell antigen 2 (BDCA2) modulator antibody portfolio | Centessa to receive $7 million upfront

🇩🇪 Boehringer Ingelheim and 🇺🇸 IBM partner to advance generative AI models for antibody development | undisclosed terms

Subscribe to our newsletter for more partnering updates! 
🔗 https://lnkd.in/dsgz62YY

#deals #partnering #mergers #acquisitions #biotech

Have you heard about what’s been going on in the world of biotech over the past week? 🗞️

Catch up on the latest biotech news with Labiotech. The past week, there’s been buzz about Vivodyne developing lab-grown human organs, Boehringer Ingelheim acquiring T3 Pharmaceuticals AG in a $500 million buyout, successful diabetic retinopathy and NASH trials ✅, and new cancer drugs in the making. 💊

 For your weekly dose of news in the biotech space, read our latest article! 👇
https://lnkd.in/d_AAVbiB

#BiotechNews #Biotech #Biopharma #ClinicalTrials #Deals #Partnerships #Research

Did you know that women are 10 times more likely to develop primary biliary cholangitis than men? 👀

Primary biliary cholangitis is a genetic, chronic, progressive, autoimmune liver disease that is characterized by the chronic inflammation and scarring of the bile ducts within the liver. 

There are several challenges when it comes to developing new drugs to treat the condition. Diagnostic delay is a major problem, and so is drug development. 💊

👩‍🔬 Researchers at French biopharmaceutical company Ipsen have developed a new class of medicines that target bile acid metabolism inflammation in primary biliary cholangitis. The company is looking to get the drug approved soon.

We spoke to Jennifer Schranz M.D., SVP and global head of rare diseases in the R&D division at Ipsen about their drug that has just undergone a phase 3 trial. 🎙️ Tune into the latest episode of the Beyond Biotech Podcast to find out about this new class of drugs that could change the game for primary biliary cholangitis! 👇

https://lnkd.in/dcZhqrDE

#LiverDisease #Research #Biotech #Biopharma #PrimaryBiliaryCholangitis

American Association for the Study of Liver Diseases (AASLD) | EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER 


💰 Biotech's Top Investments This Week! 🚀

🇺🇸 Arvinas | $350 million PIPE | targeted protein degraders | phase 3 in ER+/HER2 breast cancer

🇺🇸 Aro Biotherapeutics | $41.5 million series B | targeted genetic medicine | phase 1 in Pompe disease

🇺🇸 Vivodyne | $38 million seed | artificial intelligence (AI)-based drug discovery

🇳🇱 🇨🇭 Cradle | $24 million series A | AI-based protein engineering

🇬🇧 Harness Therapeutics | £4 million ($5.07 million) funding | RNA-targeted treatments | preclinical in Huntington’s Disease

Subscribe to our newsletter for more fundraising updates!
🔗 https://lnkd.in/dsgz62YY

#fundraising #funding #biotech #venturecapital #fundinground #biotechstartup #seriesa #seriesb #seriesc #investors #IPO #seedfunding

Did you know that an Alzheimer’s vaccines could be cheaper than other treatment options? 💉

As the price of various Alzheimer’s drugs poses a barrier for people to access them, vaccines could make treating the disease more affordable for millions. 💲✂️

Currently, Vaxxinity and AC Immune are among a few companies that are focused on delivering this form of immunotherapy. Their vaccine candidates target disease-causing proteins in the brain, by inducing an immune response. 🧠

With an aim to eliminate side effects that have been associated with Alzheimer’s vaccines in the past, these biotechs have taken their candidates to the clinic. 🏥

Find out about how vaccines could change the game for Alzheimer’s care in our latest article! 👇

https://lnkd.in/dPCreYj3

#Alzheimers #AlzheimersDisease #AlzheimersResearch #Biotech #Vaccines #Alzheimers
Alzheimer's Association®| Alzheimer's Society | Alzheimer's Disease International

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