89bio, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapies for the treatment of liver and cardio-metabolic diseases. Its lead product candidate is pegozafermin, a glycoPEGylated analog of fibroblast growth factor 21 for the treatment of nonalcoholic steatohepatitis. The company also intends to develop pegozafermin for the treatment of severe hypertriglyceridemia. 89bio, Inc. was incorporated in 2018 and is headquartered in San Francisco, California.

89bio, Inc.

89bio is a clinical-stage biopharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of liver and cardio-metabolic diseases. The company’s lead product candidate, BIO89-100, is a specifically engineered glycoPEGylated analog of FGF21. BIO89-100 is being developed for the treatment of nonalcoholic steatohepatitis (NASH) and severe hypertriglyceridemia (SHTG). Recent Phase 1b/2a data show BIO89-100 demonstrated a favorable safety and tolerability profile and robust reductions in liver fat and key lipid markers when dosed weekly or once every two weeks in patients with NASH. BIO89-100 is currently in a Phase 2 trial for the treatment of SHTG. 89bio is headquartered in San Francisco with operations in Herzliya, Israel.

Our culture is best described by our values:
•	Always putting the patient first
•	Operating with the highest integrity and ethical standards at all times
•	Being authentic in all our transactions
•	Acting as a team – collaborating, respecting and caring for one another
•	Being entrepreneurial and passionate in our tasks
•	Being scientific and rational in our thought process and decision-making


K2 HealthVentures

Longitude Capital

OrbiMed

Pontifax

RA Capital Management

89bio

It’s #NationalTriglycerides day: do you know your numbers? Our #triglyceride levels play a key role in living a healthy lifestyle. Elevated triglyceride levels can increase the risk of several conditions, including #CardiovascularDisease and #MetabolicSyndrome.
 
Learn more about Severe Hypertriglyceridemia or #SHTG and 89bio’s mission to develop treatment options: https://lnkd.in/gE7AwYWu

Our investigational FGF21 analog has received the European Medicines Agency Priority Medicines (PRIME) status in patients with non-cirrhotic #MASH with fibrosis and MASH with compensated cirrhosis. This designation was supported by the positive data from our Phase 2b ENLIVEN trial. 

Learn more about the PRIME status and what this means for us: https://lnkd.in/gSDeAeAK

#NASH #MASH #Innovation #the89way
 


We’re excited to announce the initiation of our Phase 3 ENLIGHTEN-Fibrosis trial, which will evaluate the efficacy and safety of our investigational fibroblast growth factor 21 (FGF21) analog in patients with metabolic dysfunction-associated steatohepatitis (MASH) and fibrosis. This new phase marks an inspiring milestone in our progress toward developing meaningful medicines. 

To learn more, read our release: https://lnkd.in/eG6UuC-P 
 
#NASH #MASH #ClinicalTrials #Innovation

Join our growing team at 89bio! Our team of experts embrace a start-up mindset, cultivate an entrepreneurial spirit and are driven to create the best opportunities for our hard-working team of 89ers. If this sounds like you, and you’re passionate about developing innovative therapies for #CardioMetabolic diseases, check out our open roles and learn more about #the89way: https://lnkd.in/gnP5i8-n

#HealthcareJobs #Hiring

	Dec '18	Dec '19	Dec '20	Dec '21	Dec '22	Dec '23
asset turnover
cash per share	2.45 -	39.83 1,524.98%	19.34 51.44%	12.39 35.92%	5.41 56.37%	8.13 50.45%
company equity multiplier	-0.71 -	1.06 250.04%	1.04 2.11%	1.29 23.99%	1.30 0.53%	1.11 14.23%
days of inventory outstanding
days of payables outstanding						11.48K -
days of sales outstanding
dividend yield						0.00 -
ebit per revenue
ebt per ebit	1.07 -	2.15 101.61%	1.00 53.24%	1.01 0.17%	-1.00 199.18%	0.91 191.70%
effective tax rate	-0.00 -	-0.00 119.79%	0.00 131.24%	0.00 36.79%	-0.00 111.44%	-0.03 14,909.26%
enterprise value multiple	-5.55 -	1.19 121.46%	-3.80 418.79%	-1.46 61.46%	-3.99 172.57%	-3.35 15.97%
fixed asset turnover
free cash flow per share	-2.73 -	-10.92 300.18%	-2.88 73.61%	-3.82 32.65%	-2.33 39.06%	-1.82 22.09%
gross profit margin
interest coverage					53.20 -	-42.17 179.26%
inventory turnover
long term debt to capitalization				0.12 -	0.12 2.14%	0.04 61.83%
net income per ebt	1.00 -	1.00 0.21%	1.00 0.50%	1.00 0.04%	1.00 0.18%	1.03 2.78%
net profit margin
operating cash flow per share	-2.72 -	-10.86 299.25%	-2.87 73.53%	-3.82 32.90%	-2.33 39.02%	-1.82 22.09%
operating profit margin
payables turnover						0.03 -
pretax profit margin
price fair value	-5.94 -	0.69 111.54%	1.93 181.92%	2.09 7.96%	2.92 39.93%	1.48 49.20%
receivables turnover
return on assets	-1.42 -	-0.60 57.77%	-0.23 60.98%	-0.55 136.61%	-0.52 6.58%	-0.24 54.00%
return on capital employed	-2.16 -	-0.30 86.29%	-0.24 17.90%	-0.63 158.28%	0.59 194.53%	-0.27 144.94%
return on equity	1.01 -	-0.64 163.37%	-0.24 61.80%	-0.72 193.38%	-0.67 6.08%	-0.27 60.54%
total debt to capitalization				0.13 -	0.12 12.61%	0.05 61.39%

COM:89BIO

89Bio

Last Close

8.38

22/11 21:00

Market Cap

851.02M

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477.49K

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