Capstan is a biotechnology company with a mission to multiply the therapeutic possibilities for patients by developing targeted in vivo RNA technologies. The core platform technology comprises proprietary targeted lipid nanoparticles (tLNP) that are composed of LNPs conjugated with a recombinant protein binder, such as a monoclonal antibody. tLNPs are designed to deliver payloads, including mRNA or gene editing tools, capable of reprogramming specific cell types in vivo. The platform technology has the potential to generate transformative therapies with possible applications across a broad range of disease areas, including autoimmune disorders, oncology, fibrosis, and monogenic blood disorders. For more information, please visit www.capstantx.com. 

Vida Ventures

Leaps by Bayer

Bristol-Myers Squibb

Alexandria Venture Investments

Eli Lilly & Company Foundation

Novartis Venture Fund

OrbiMed

Pfizer Venture Investments

Polaris Partners

RA Capital Management

Capstan Therapeutics

This week Capstan CSO and EVP of R&D, Adrian Bot, M.D., Ph.D., will participate in a fireside chat at the 2nd Annual H.C. Wainwright & Co., LLC Cell Therapy Virtual Conference, where he will discuss our mission to multiply the possibilities for patients through our targeted in vivo RNA-based approach.

It’s an exciting time to be on Team Capstan as we look to advance our in vivo CAR-T lead program, CPTX2309, using the proceeds of our recently announced oversubscribed Series B financing: https://lnkd.in/eN5WcfkX
 
We are hiring at multiple levels across various disciplines including in vitro pharmacology, analytical development, formulation & process development, and more.
 
Interested in joining our creative, collaborative team committed to pioneering a new frontier of medicine? Read more about our open positions and apply here: https://lnkd.in/eiU8hT7y 

Today we announced the successful closing of an oversubscribed Series B financing of $175 million, which will support the advancement of our lead program, CPTX2309, through clinical proof-of-concept studies for #autoimmune disorders. We are also pleased to welcome Nanna Lüneborg, Ph.D., MBA, to our Board of Directors.
 
CPTX2309 is the flagship of our tLNP platform, delivering an mRNA payload encoding for an anti-CD19 chimeric antigen receptor to CD8-expressing T cells, effectively engineering CAR-T cells in vivo for the treatment of autoimmune disorders.
 
We thank each of our investors for believing in and supporting our mission to multiply the therapeutic possibilities for patients by developing targeted in vivo RNA-based therapies.

Read more in our press release: https://lnkd.in/eN5WcfkX

Forbion, Johnson & Johnson Innovation JJDC Inc, Mubadala, Perceptive Advisors, Sofinnova Investments 

A sincere congratulations is in order for our very own President and Chief Executive Officer, Dr. Laura Shawver, who was recently recognized as the 2024 Duane Roth Endowed Award Lecture recipient for her contributions in the oncology space.
 
Dr. Shawver’s work as a scientist, leader, patient and patient advocate spans across decades and has led to new paradigms in cancer research and support for patients.
 
She has touched the lives of so many and we are thankful to have her as the leader of Team Capstan. Read more about Dr. Shawver and the Duane Roth Award here: https://lnkd.in/gMfgjRXc

Happy #InternationalWomensDay! We are thankful for the committed, collaborative and creative women on Team Capstan who drive forward our mission to multiply the therapeutic possibilities for patients by developing targeted in vivo RNA-based therapies. #IWD2024 

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Capstan Therapeutics is a biotechnology company that collects and processes personal information from various sources, including directly from individuals, third parties, and automatically through cookies. The company uses this information for various purposes, such as providing information, responding to inquiries, and improving website functionality.

Senior Director, Head of Cell Engineering

Business Partner

Head, Genome Engineering Platform & Cell Therapy

Associate Director of Gene Therapy, R&D

Associate Director, Gene Editing

Director, Research and Development

Research Associate, Research Faculty

Research Associate

Genome Engineering Leader, Cell & Gene Therapies

Xianghong Li

Director, CMC Operations

Associate Director, CMC Operations

Senior Manager, CMC Operations

Manager, Formulation Production

Research Associate, Formulation Development

Research Intern, Pharmaceutical Development

Chemical Engineering Senior Process Laboratory & Design

Diversity Peer Educator

Director, CMC Operations at Capstan Therapeutics

Jerel Vega

Sr. Director, Program Manager

Sr. Director, Program Management

Sr. Director, Project Management

Director of Project Mangement

Project Manager

Sr. Project Manager

Program Manager

Laura Kuhn

Senior Director Information Technology

Owner

Sr. Director, Information Technology

Director, Information Technology

Sr. Director, IT Operations

Director IT Operations

IT and Data Integration Manager

Systems Engineer

RallyNW Volunteer Coach

Network Engineer

Network Administrator

Programmer Analyst

Team in Training Volunteer

Network Technician

Branch Director

eCorps.Wa Volunteer

IT Executive | Inclusive Leader | IT Roadmap Specialist | Fledgling Martial Artist

Jason Ruiz

Senior Director, Analytical and CMC Operations

CMC/Supply, Director

Associate Director, CMC

Senior Manager, Analytical/CMC

Associate Director of QC

CMC Pharmaceutical Development

Director of Analytical Services

Scott Roberts

Senior Director, Corporate Development

Director, Program Management

Director, Product Development

Associate Director, Process Engineering and Product Development

Senior Manager, Process Engineering

Senior Process Engineer

Process Engineer

Engineer II

Engineer I

Associate Engineer

Research Assistant

Teaching Assistant

ORDP Intern

Course Advisor, Bioengineering

Intern

Atia Naim

Head of Analytical Operations

Director

Associate Director

Principal Scientist

Senior Scientist

Scientist

Graduate Intern

Graduate Student Research Assistant

Summer Engineering Intern

Senior Director

David Chu

Chief Technology Officer

Vice President, Technology Innovation and Development

Senior Director, Pharmaceutical Development

Director of Research, Head Formulation and Analytical Development

Associate Director Formulation Development

Senior Manager, Formulation Development

Principal Scientist, Formulation Development

Chief Scientist/ Senior Scientist, Formulation Development

Staff Scientist/Postdoctoral Research Associate

Priya Karmali

Scientific Co-Founder

Research Assistant Professor

Research Assistant Professor at University of Pennsylvania

Hamideh Parhiz

Founding CEO

Founder

Interim Chief Executive Officer and co-founder

Chairman of the Board

Board member

Biotech Executive

Christian Homsy

Associate Director, Human Resources

Talent Acquisition Consultant

Talent Acquisition & HR

Senior Manager, HR and TA Business Partner R&D

Senior Talent Acquisition Partner

Christopher R.

Chief Medical Officer

Venture Partner

Executive Chairman

Vice President, Medical Research

Assistant Professor of Medicine

Fellow, Cardiovascular Medicine

Resident, Internal Medicine

Chief Medical Officer, Capstan Therapeutics

Ramin Farzaneh-Far

Senior Director Quality Assurance

Senior Director Quality

Director Quality Assurance

Senior Manager QA Compliance

Senior Manager Quality Assurance

Senior Director Quality at Prometheus Biosciences

Ryan Strazik

Member Board of Directors

Board Chair

Member Board Of Directors

Founder and Director

Chief Executive Officer

President and CEO

President and various positions

scientist

President and Chief Executive Officer

Laura Shawver

Associate Director, Antibody CMC

Manager, GMP Operation

Manager, Recombinant Proteins Manufacturing

Recombinant Antibody Scientist

Fellow

Director and Medical Writer

Postdoctoral Research Fellow

Researcher PHD Student

Undergraduate Research Training (Honors Project)

Undergraduate Research Opportunities Project (UROP) training

Yong

Director Capstan Therapeutics

Co-Founder, Chief Executive Officer

Co Founder, Chief Executive Officer Avenzo Therapeutics

Athena Countouriotis

Founding Chief Scientific Officer and Executive Vice President of R&D

Section Editor

Research Head, Santa Monica

Vice President, Translational Medicine

Editor in Chief

Chief Scientific Officer

Chief Scientific Officer and Executive Vice President of R&D at Capstan Therapeutics

Adrian Bot

Senior Director - Head of Product Discovery

Postdoctoral Fellow

Post-doctoral Researcher

Head of Product Discovery at Capstan Therapeutics

Stuart Sievers

Senior Director, Pharmacology and Toxicology

Associate Director, North America, Immunology and Immunotoxicology, Labcorp Drug Development

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Capstan Therapeutics