Capstan is a biotechnology company with a mission to multiply the therapeutic possibilities for patients by developing targeted in vivo RNA technologies. The core platform technology comprises proprietary targeted lipid nanoparticles (tLNP) that are composed of LNPs conjugated with a recombinant protein binder, such as a monoclonal antibody. tLNPs are designed to deliver payloads, including mRNA or gene editing tools, capable of reprogramming specific cell types in vivo. The platform technology has the potential to generate transformative therapies with possible applications across a broad range of disease areas, including autoimmune disorders, oncology, fibrosis, and monogenic blood disorders. For more information, please visit www.capstantx.com. 

Vida Ventures

Leaps by Bayer

Bristol-Myers Squibb

Alexandria Venture Investments

Eli Lilly & Company Foundation

Novartis Venture Fund

OrbiMed

Pfizer Venture Investments

Polaris Partners

RA Capital Management

Capstan Therapeutics

This week Capstan CSO and EVP of R&D, Adrian Bot, M.D., Ph.D., will participate in a fireside chat at the 2nd Annual H.C. Wainwright & Co., LLC Cell Therapy Virtual Conference, where he will discuss our mission to multiply the possibilities for patients through our targeted in vivo RNA-based approach.

It’s an exciting time to be on Team Capstan as we look to advance our in vivo CAR-T lead program, CPTX2309, using the proceeds of our recently announced oversubscribed Series B financing: https://lnkd.in/eN5WcfkX
 
We are hiring at multiple levels across various disciplines including in vitro pharmacology, analytical development, formulation & process development, and more.
 
Interested in joining our creative, collaborative team committed to pioneering a new frontier of medicine? Read more about our open positions and apply here: https://lnkd.in/eiU8hT7y 

Today we announced the successful closing of an oversubscribed Series B financing of $175 million, which will support the advancement of our lead program, CPTX2309, through clinical proof-of-concept studies for #autoimmune disorders. We are also pleased to welcome Nanna Lüneborg, Ph.D., MBA, to our Board of Directors.
 
CPTX2309 is the flagship of our tLNP platform, delivering an mRNA payload encoding for an anti-CD19 chimeric antigen receptor to CD8-expressing T cells, effectively engineering CAR-T cells in vivo for the treatment of autoimmune disorders.
 
We thank each of our investors for believing in and supporting our mission to multiply the therapeutic possibilities for patients by developing targeted in vivo RNA-based therapies.

Read more in our press release: https://lnkd.in/eN5WcfkX

Forbion, Johnson & Johnson Innovation JJDC Inc, Mubadala, Perceptive Advisors, Sofinnova Investments 

A sincere congratulations is in order for our very own President and Chief Executive Officer, Dr. Laura Shawver, who was recently recognized as the 2024 Duane Roth Endowed Award Lecture recipient for her contributions in the oncology space.
 
Dr. Shawver’s work as a scientist, leader, patient and patient advocate spans across decades and has led to new paradigms in cancer research and support for patients.
 
She has touched the lives of so many and we are thankful to have her as the leader of Team Capstan. Read more about Dr. Shawver and the Duane Roth Award here: https://lnkd.in/gMfgjRXc

Happy #InternationalWomensDay! We are thankful for the committed, collaborative and creative women on Team Capstan who drive forward our mission to multiply the therapeutic possibilities for patients by developing targeted in vivo RNA-based therapies. #IWD2024 

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Healthcare

Daniel J. Wikenheiser

Operations

Jerel Vega

Business Management

Paola Sette

Associate Director, Bioinformatics

Shaun Grosskurth

Senior Director - Head of Product Discovery

Stuart Sievers

Engineering

Xianghong Li

Cory Bentley

Senior Manager, Lab and Office Operations

Flora Huynh

Jessie Phan

Michelle Nguyen

Nanna Lüneborg

Miguel Arcinas

Senior Vice President of Corporate Development

Ramin Farzaneh-Far

Chief Medical Officer

Athena Countouriotis

Director

Priya Karamali

Chief Technology Officer

Haig Aghajanian

Co-Founder and Vice President of Research

Justin Thacker

Chief Financial Officer

Jeffrey Pepe

General Counsel

West Coast Therapeutics Companies

Health Care Early Stage Companies With More Than 50 Employees

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Capstan Therapeutics is advancing precision in vivo cell engineering to develop therapeutics for a broad range of disease categories with unmet or underserved clinical need.

Series B - Capstan Therapeutics

Series A - Capstan Therapeutics

Seed Round - Capstan Therapeutics

San Diego

California

United States

North America

Capstan Therapeutics Presents Preclinical Data on Lead In Vivo CAR-T Candidate, CPTX2309, at American College of Rheumatology (ACR) Convergence 2024

Endpoints 11 winner Capstan Therapeutics: Trying to win the in vivo CAR-T race

Capstan Therapeutics to Participate in 45th Annual Goldman Sachs Global Healthcare Conference

Capstan Therapeutics’ Post

Capstan Scores $175M Series B

Capstan Therapeutics–SEVERAL: investment, 202403 financing round Series B $175m led by RA Capital Management

The 10 Biggest Rounds Of March: Wonder, Biotech Headline Big Month

An in vivo CAR-T product candidate designed for autoimmune disorders, utilizing targeted lipid nanoparticles to deliver mRNA encoding for an anti-CD19 CAR to CD8-expressing T cells.

A core technology platform comprising proprietary targeted lipid nanoparticles designed for in vivo delivery of mRNA or gene editing tools to reprogram specific cell types.

A therapeutic approach that delivers mRNA-encoded CARs to specific immune cells, enabling them to target and eliminate pathogenic cells.

A method that delivers mRNA-encoded gene editing machinery to pathogenic cells, allowing for the modification of the cells’ DNA to treat genetic diseases.

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Senior Director, Head of Cell Engineering

Business Partner

Head, Genome Engineering Platform & Cell Therapy

Associate Director of Gene Therapy, R&D

Associate Director, Gene Editing

Director, Research and Development

Research Associate, Research Faculty

Research Associate

Genome Engineering Leader, Cell & Gene Therapies

Director, CMC Operations

Associate Director, CMC Operations

Senior Manager, CMC Operations

Manager, Formulation Production

Research Associate, Formulation Development

Research Intern, Pharmaceutical Development

Chemical Engineering Senior Process Laboratory & Design

Diversity Peer Educator

Director, CMC Operations at Capstan Therapeutics

Sr. Director, Program Manager

Sr. Director, Program Management

Sr. Director, Project Management

Director of Project Mangement

Project Manager

Sr. Project Manager

Program Manager

Laura Kuhn

Senior Director Information Technology

Owner

Sr. Director, Information Technology

Director, Information Technology

Sr. Director, IT Operations

Director IT Operations

IT and Data Integration Manager

Systems Engineer

RallyNW Volunteer Coach

Network Engineer

Network Administrator

Programmer Analyst

Team in Training Volunteer

Network Technician

Branch Director

eCorps.Wa Volunteer

IT Executive | Inclusive Leader | IT Roadmap Specialist | Fledgling Martial Artist

Jason Ruiz

Senior Director, Analytical and CMC Operations

CMC/Supply, Director

Associate Director, CMC

Senior Manager, Analytical/CMC

Associate Director of QC

CMC Pharmaceutical Development

Director of Analytical Services

Scott Roberts

Senior Director, Corporate Development

Director, Program Management

Director, Product Development

Associate Director, Process Engineering and Product Development

Senior Manager, Process Engineering

Senior Process Engineer

Process Engineer

Engineer II

Engineer I

Associate Engineer

Research Assistant

Teaching Assistant

ORDP Intern

Course Advisor, Bioengineering

Intern

Atia Naim

Head of Analytical Operations

Associate Director

Principal Scientist

Senior Scientist

Scientist

Graduate Intern

Graduate Student Research Assistant

Summer Engineering Intern

Senior Director

David Chu

Vice President, Technology Innovation and Development

Senior Director, Pharmaceutical Development

Director of Research, Head Formulation and Analytical Development

Associate Director Formulation Development

Senior Manager, Formulation Development

Principal Scientist, Formulation Development

Chief Scientist/ Senior Scientist, Formulation Development

Staff Scientist/Postdoctoral Research Associate

Priya Karmali

Scientific Co-Founder

Research Assistant Professor

Research Assistant Professor at University of Pennsylvania

Hamideh Parhiz

Founding CEO

Founder

Interim Chief Executive Officer and co-founder

Chairman of the Board

Board member

Biotech Executive

Christian Homsy

Associate Director, Human Resources

Talent Acquisition Consultant

Talent Acquisition & HR

Senior Manager, HR and TA Business Partner R&D

Senior Talent Acquisition Partner

Christopher R.

Venture Partner

Executive Chairman

Vice President, Medical Research

Assistant Professor of Medicine

Chief Medical Officer, Capstan Therapeutics

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