Caribou Biosciences, Inc., a clinical-stage biopharmaceutical company, engages in the development of genome-edited allogeneic cell therapies for the treatment of hematologic malignancies and solid tumors in the United States and internationally. Its lead product candidates are CB-010, an allogeneic anti-CD19 CAR-T cell therapy that is in phase 1 clinical trial to treat relapsed or refractory B cell non-Hodgkin lymphoma; and CB-011, an allogeneic anti-BCMA CAR-T cell therapy for the treatment of relapsed or refractory multiple myeloma. The company also develops CB-012, an allogeneic anti-CD371 CAR-T cell therapy for the treatment of relapsed or refractory acute myeloid leukemia; and CB-020, an allogeneic CAR-NK cell therapy for the treatment of solid tumors. It has collaboration with AbbVie Manufacturing Management Unlimited Company to develop CAR-T cell therapies. The company was incorporated in 2011 and is headquartered in Berkeley, California.

James Berger

Martin Jinek

Jennifer Doudna

Rachel E. Haurwitz

Caribou Biosciences, Inc.

Pairwise focuses on the application of CRISPR technology in food and agriculture, delivering unique varieties of crops for growers and consumers.

Tom Adams

Haven Baker

Pairwise

Caribou is a clinical-stage biopharmaceutical company, founded by pioneers in CRISPR genome editing, leveraging our proprietary technology to develop genome-edited off-the-shelf immune cell therapies for the treatment of cancer. We believe that cell therapies are critical now and for the future of cancer therapy and that advanced genome editing is necessary to develop sophisticated cell therapies to treat a variety of malignancies. We are developing a pipeline of genome-edited, off-the-shelf CAR-T and CAR-NK cell therapies for a range of tumor types. 

Our mission is to develop innovative, transformative therapies for patients with devastating diseases through novel genome editing. 

Members of the Caribou herd open their minds to new ideas and welcome diverse perspectives. We proudly assert that teams do their best work when their members are personally engaged, their ideas are taken seriously, their contributions are recognized, and their needs are met. 

Interested in joining our team? Please check out our jobs at
https://cariboubio.bamboohr.com/jobs/

Intellia Therapeutics

Janus Henderson Investors

LifeSci Venture Partners

Maverick Ventures

Heritage Group

Ridgeback Capital

Farallon Capital Management

AbbVie Biotech Ventures

Adage Capital Management

Avego Bioscience Capital

Avidity Partners

Caribou Biosciences

Join our VP, clinical development Socorro Portella, MD, and director of clinical research Ashley Hammad, AG-CNS, tomorrow at the #CRISPR 2.0 workshop, A 101 in First-in-Human CRISPR Trials taking place at 1:00pm ET tomorrow.

Kevin Liao, associate director, supply chain, will lead a workshop at the Donor Selection and Cell Source Summit. Join him on Tuesday, Nov. 28 at 1 pm ET.

The Caribou team will be presenting at the 4th Annual #CRISPR 2.0 Conference next week in Boston! Socorro Portella, MD, and Ashley Hammad, RN, will lead a workshop on Tuesday, Nov. 28 at 1 pm ET and Enrique Zudaire, PhD, will present on Thursday, Nov. 30 at 11:45 am ET. #CRISPR #CARTcell

Members of the Caribou team enjoyed an incredible night celebrating the accomplishments of Paul Donohoue, associate director of platform discovery and co-inventor of Caribou’s chRDNA technology, and the other nine esteemed winners of the 2023 Biocom California Catalyst Awards. Join us, once again, in congratulating Paul on this very well-deserved recognition of his innovation and scientific advancement in #CRISPR genome-editing technologies.  

Want to learn more about one of Paul's inventions? Check it out here: https://lnkd.in/gbEsNexH

Tune in for our company presentation by President and CEO Rachel Haurwitz, PhD, at the Jefferies London Healthcare Conference. A link to the webcast is on the investor section of our website: https://lnkd.in/gjSwyTzc

Caribou would be nothing without the incredible people who make up #theHerd. We are starting a new series to highlight Caribou’s leaders and explore their team’s impact, why they joined Caribou, and what drives them to develop allogeneic CAR-T cell therapies. We start the series with Enrique Zudaire, PhD. Watch the video to learn more about Kike!

Ahead of Veterans Day, we’d like to extend our gratitude to American veterans, especially those who are part of #TheHerd. Thank you for your service. #VeteransDay

This year, we have advanced our programs to build value across the pipeline and position Caribou as a leader in the allogeneic CAR-T cell therapy space. Learn more about our progress in our Q3 2023 financial results here: https://lnkd.in/gcXfDtbf #CRISPR #CARTcelltherapy

We are excited to announce the appointment of Jagannath Sundar, MD, to our scientific advisory board. We welcome Dr. Jagannath and his insights as a renowned expert in the treatment of #multiplemyeloma.
https://lnkd.in/eM47dKkA

Don’t miss Caribou Biosciences at upcoming investor conferences—tune in to available webcasts here: https://lnkd.in/gjSwyTzc

Metric
Company Name	Caribou Biosciences, Inc.	Pairwise
Symbol	CRBU
MSH ID	COM:CARIBOUBIO	COM:PAIRWISE
Market	STOCKS	PRIVATE
Sector	Healthcare	Consumer Goods
Industry	Biotechnology	Food & Agriculture
Country	US	US
Stage
Employee Count	158	168
Website	cariboubio.com	pairwise.com
LinkedIn	caribou-biosciences	pairwise-plants
Founders

Metric
Market Cap	153.54M	205M
Enterprise Value
Monthly Web Traffic	6.55K	7.21K
Web Traffic Growth	0.38	0.63
Valuation
Raised Capital	125M

Metric
Revenue	34.48M
Revenue (LTM)
Revenue (NTM)
Gross Profit	30.95M
EBITDA	-112.53M
Operating Income	-116.06M
Net Income	-102.07M
EPS	-1.38
Diluted EPS	-1.38
Revenue 2022
Revenue 2023
Revenue 2024
Revenue 2025
Revenue 2026

Metric
Revenue Growth (LTM)
Revenue Growth (NTM)
Gross Profit Growth (LTM)
EBITDA Growth (LTM)
Net Income Growth (LTM)
14-Day Growth Score
28-Day Growth Score
90-Day Growth Score
365-Day Growth Score

Metric
Gross Profit Margin	0.86
Operating Profit Margin	-3.37
EBITDA Margin	-3.26
Net Profit Margin	-2.87
Return on Equity	-0.30
Return on Assets	-0.22
Return on Capital Employed	-0.28

COM:CARIBOUBIO

Caribou Biosciences

Last Close

1.98

22/11 21:00

Market Cap

153.54M

Beta: -

Volume Today

989.16K

Avg: -

Company Overview

Market Metrics

Financial Performance

Growth Metrics

Profitability Ratios

Valuation Multiples

Operational Metrics

Cash Flow Metrics

Balance Sheet Metrics

Efficiency Metrics

Metric
P/E Ratio	-6.14
P/B Ratio	1.41
Revenue Multiple (LTM)
Revenue Multiple (NTM)
EBITDA Multiple (LTM)
EBITDA Multiple (NTM)
Price to Sales Ratio	13.61
EV Multiple	-1.24

Metric
Days Sales Outstanding	54.16
Days Payables Outstanding
Days Inventory Outstanding
Operating Cycle	40.85
Cash Conversion Cycle	-139.62
Asset Turnover	0.09

Metric
Operating Cash Flow	-93.29M
Free Cash Flow	-104.90M
Cash Flow to Debt	-3.39
Operating Cash Flow/Sales	-2.71
Free Cash Flow Yield	-0.18

Metric
Cash & Equivalents	51.16M
Accounts Receivable	805K
Inventory
Goodwill
Debt to Capitalization	0.08
Debt to Assets	0.06
Current Ratio	14.27
Quick Ratio	11.75

Metric
Rule of 40 (LTM)
Rule of 40 (NTM)
Stock Comp to Revenue	0.38
R&D to Revenue	3.08
SG&A to Revenue	1.08