DNA Script was created to revolutionize DNA synthesis with enzymes. Our core R&D efforts have produced innovations in enzyme engineering, surface and nucleotide chemistries, and instrumentation. The integration of these innovations has resulted in SYNTAX™️, the world’s first benchtop DNA printer powered by enzymatic technology. With continued advancement and innovation, we believe DNA Script’s enzymatic DNA synthesis technology is poised to become the engine of genomics research and personalized medicine.

Hedonova

Sofinnova Partners

Kurma Partners

Illumina Ventures

Agilent Technologies

Danaher Life Science

Bpifrance

Casdin Capital

EQT life science

M Ventures

Baillie Gifford

eureKARE

Fidelity Management and Research Company

Catalio Capital Management

Coatue

Columbia Threadneedle Investments

HealthCor

HealthCor Partners

Irving Investors

DNA Script

An international group, including researchers at the Wyss Institute at Harvard University for Biologically Inspired Engineering, Dana-Farber Cancer Institute, and Boston Children's Hospital, extended DoriVac, a #DNA origami-based #vaccine platform, to infectious diseases.
 
By conjugating DoriVac with heptad repeat 2 (HR2) peptides, which play a role in fusing the viral and host cell membranes and are conserved across a host of viral species, the group observed that DoriVac induced neutralizing antibodies and CD4+ and CD8+ T-cell response in mice against SARS-CoV-2, HIV and Ebola. Immune response was also induced in a human lymph-node-on-chip model.
 
Taken together, the results suggest DoriVac, when conjugated to viral antigens, holds promise for inducing robust immune response and its flexible, modular nature may make it a good candidate system for responding to future global disease outbreaks.
#pandemic #immuneresponse #syntheticbiology
 
https://lnkd.in/epbFpdBR

Day 2 at PepTalk! Come stop by booth #714 if you're interested in learning more about enzymatic #DNA synthesis. Michael Delaney Sullivan, Melissa Gentz

A group at Dana-Farber Cancer Institute , along with researchers at the Broad Institute of MIT and Harvard,  and Massachusetts General Hospital Cancer Center, previously reported on a new technique called MAESTRO (Minor Allele Enriched Sequencing Through Recognition Oligonucleotides) for assaying for minimal residual disease (#MRD) using #cfDNA. 
 
In a new study, this group expanded on MAESTRO with a new approach called MAESTRO-Pool. This technique pools MAESTRO probes from all patients assayed, which allowed the researchers to assay over 23,000 mutations in 9 melanoma patients over several cfDNA samples per patient. By pooling, the researchers were able to quantify MRD in matched patients as well as the rate of false positives in unmatched patients.
 
The assay showed a 10- to 100-fold improvement in sensitivity versus existing MRD tests and showed high specificity for detecting MRD.
#cancer #oligonucleotides #assaydevelopment
 
https://lnkd.in/g8z26pQG

We’ll be at PepTalk in San Diego from January 16th to 19th, and we hope to see you there! Come find Michael Delaney Sullivan and Melissa Gentz at Booth 714 to learn more about the SYNTAX System.

As we bring 2023 to a close, we reflect on this past year and the promise of benchtop enzymatic #DNA synthesis (EDS), and look back at a publication by a group at US Army which assessed benchtop #EDS for gene assembly applications. 
 
The study concluded that EDS-derived #oligonucleotides could be obtained in half the time of commercially-synthesized oligos, yielded functional gene product, and that EDS clearly reduced the waste stream compared to using traditional chemical synthesis methods for oligo production.
#oligo #DNAScript #genesynthesis #syntheticbiology
 
https://bit.ly/41GoPFD

Iridia is a deoxyribonucleic acid (DNA) data storage platform. It stores medical records, financial information, and other sensitive data in a secure way.

Iridia

DNA Script is a company focused on revolutionizing DNA writing with enzymes, particularly through the development of the SYNTAX System, the world’s first DNA printer powered by enzymatic technology. The company values excellence, transparency, and benevolence in its operations.

Sr. HR Business Partner

Sr. HR Business Partner & Organizational Development

Sr. Human Resources Manager

Human Resources Manager

Sr. Recruitment & Employee Engagement Specialist

Manager - Practice Lead with Procurement & Supply Chain

Recruiter

Jillian Williams

Creative Director

Brand & Design Director

Senior Creative Lead

Visual Creative Lead

Creative Director | Brand & Business Design

Ugo Mauro

Co-founder & CTO

Engineer

Analyst

Xavier Godron

Senior Director Product Development

Senior Director R&D Assay Development and System Validation

Director R&D Molecular Biology

Scientific Consultant

Senior Scientist

Research Scientist

Senior Director Product Development at DNA Script

Allison Mallory

Associate Director Engineering

Principal Mechanical Engineer

Staff Mechanical Engineer

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Design  Engineer

Engineering Lead

Engineer I

Scientist I

World Services Intern

Project Engineer

Applications Engineer

Help Desk Coordinator

Associate Director, Engineering

Sean McCusker

Director of Product Management

Responsable Marketing & Ligne de Produits Senior

Responsable Business Unit

Chef de Produit Marketing Group

Chef de projet Biophotonique

Actionnaire

Directeur, Gestion de Produit Instrumental

Chiraz Khayat

Senior Director, Data Science & IT

Head, Data Analysis Core

Director, Genome Sequence Informatics

Director, Genome Informatics

Senior Scientific Manager - Production Software

Senior Software Developer

Director, Data Science - DNA Script

Lars Jorgensen

Director, System Engineering

Senior Manager - System Engineering, Verification, Validation

Lead System Engineer

Lead Engineer - Internal Service

Internal Service Engineer

Equipment Engineer

Engineer/Scientist II, QC

Engineer/Scientist I, QC

Scientist I, QC (Contractor)

Research Assistant Intern

Recreation Leader

Clerk

Associate Director - System Engineering

Ty Ego

Director, Finance Operations

Manager, Financial Operations

Senior Financial Auditor

Financial Auditor

Audit Associate

Junior Auditor

Auditeur junior

Assistant comptable

Treasurer

Director, Finance Operations @DNA Script

Ibrahim Dribine

HR Business Partner

HRBP

Recruitment & Assessment Consultant

HR Business Partner - Technical Operations / Corp Finance- HQ

HR Business Partner R&D / Technical Operations

Deputy Vice President Human Resources R&D

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HR Officer

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Ergonomist (intership)

Ergonomist (Internship)

Florence Morisseau

Associate Director, US Operations

Manager, Manufacturing Operations Team Leader

Sr. Manufacturing Supervisor

Manufacturing Supervisor-Upstream & Downstream

Site Supervisor-Gilead

Manufacturing Team Lead

Media Prep Technician

Emily Wang

Senior Director - R&D, Enzymes

Project Manager / Research Scientist

Postdoctoral associate

Graduate Research Associate / Postdoctoral Associate

Research Assistant

Research Internship in Biochemistry

Research Internship in analytical chemistry

Internship in Production

Senior Director, R&D - Enzymes

Elise Champion

Director Of Chemistry

Head Of Chemistry

Director of Chemistry, Staff Scientist

Postdoctoral Research Associate

Director of Chemistry at DNA Script

Weidong Wu

Chief Commercial Officer

SVP, Product Operations

Board Member

SVP & General Manager, Enzymes Business Unit

Sr. Director / VP / SVP, Business Operations

Director / Sr. Director, Product Management

Director, Product Commercialization

Director, Technology Transfer & Outsourcing

Business & Technology Manager

Team Leader, Process Technology

Rob Wilson

Director, Quality & Regulatory

Manager, Design Quality - Sequencing Systems

Manager, Design Quality - Design Transfer

Staff Design Quality Engineer - Design Transfer

Manufacturing Engineer

Advanced Tech R&D Engineer

Reliabilty Engineer

Associate Director, Quality & Regulatory @ DNA Script

Patrick Slane

Senior Director, Chemistry

Senior Director of Chemistry at DNA Script

Wu Weidong

Senior Director Applications

Head of R&D operations and medical development

Director of Medical Research

Director Clinical Project Management

Director- Clinical Affairs Management

Director profiling discovery and project management

Director Collaborative Therapeutics

Group leader Technology and Innovation

Researcher molecular biology and genomics

PhD Student

Florence Mahe

Senior Director Public Affairs & ESG

Global Forum on Technology synthetic biology focus group

University Lecturer

Head of Public Affairs

Member of the Internet Governance Forum (IGF) Multistakeholder Advisory Group (MAG)

Director - Innovation for All Department

🤖Global Public Affairs expert I Biotech I AI I Tech Policy Lead I Thought leadership I Board member

Sophie Peresson

Senior Director, Instrument Manufacturing

Vice President of Operations

Senior Director of Global Operations & Site General Manager

Director of Assembly Operations

Director of Operations

Breakthrough Solutions for Complex Challenges Across the Enterprise Value Chain: Operational Excellence, Innovation, Scalability, Growth, and Profitability.

Bernie Schneider

Senior Director, Head of Program Management

Senior Director of Product Development

Director of Systems Engineering

Head of Assay System Integration - Director, Development - Roche Sequencing Solutions

Director of Systems Development

Head of Assay System Integration - Senior Manager, Development - Roche Sequencing Solutions

Senior Director of Program Management

Carl Martin

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