Rockfish Bio focuses on the development of senolytic therapies for age-related diseases.

Rockfish Bio

Rockfish Bio | 692 followers on LinkedIn. Improving the quality of life by promoting healthy aging. | Rockfish Bio is a biotech company centred on the development of senolytic compounds based on a newly discovered target pathway. Our target pathway was successfully tested in 7 different cell types with a therapeutic index of up to 700. Our lead candidate RFB01016 was able to restore neuromuscular functions and massively extend the health and life span (+40 % median survival time after start of treatment) in naturally aged mice.

Biotechnology of Regeneration and Aging

Johannes Grillari

CEO for InnoFly BioCenter GmbH & Director DMPK at Rockfish Bio AG

Dirk B. Strickmann

CSO/COO of Rockfish Bio AG

Ingo Lämmermann

Scientist

Viviane Fleischhacker

🧟♂️ Auf der Jagd nach Zombiezellen 🧟♂️ - Noch ist sie ein Traum: die Unsterblichkeit. Doch mittlerweile arbeiten zahlreiche Start-ups daran, dem irdischen Dasein zumindest ein paar weitere Jährchen zu spendieren. Darunter auch das junge Wiener Unternehmen Rockfish Bio , das sich vor allem das gesunde Altern auf die Fahne geschrieben hat. Was das mit dem Fettsäurestoffwechsel und Zombiezellen zu tun hat, erklärt Mitgründer Ingo Lämmermann in meinem Artikel im Das Laborjournal . https://lnkd.in/eUK2k588

Tobias Ludwig

🔬 Innovative Ansätze für gesundes Altern: Die BOKU University hat eine zentrale Rolle bei der Erstellung eines neuen internationalen Konsenspapiers gespielt, das die Bedeutung seneszenter Zellen im Alterungsprozess beleuchtet. Diese Zellen, die infolge zellulären Stresses entstehen und chronische Entzündungen begünstigen, stehen im Zentrum innovativer therapeutischer Ansätze zur Bekämpfung altersbedingter Krankheiten. Unter der Leitung von Johannes Grillari , vom BOKU-Institut für Molekulare Biotechnologie, haben österreichische und internationale Expert*innen gemeinsam die MICSE-Leitlinien entwickelt. Diese Leitlinien definieren standardisierte Marker und Methoden zur Untersuchung seneszenter Zellen. Die Veröffentlichung der Leitlinien in der renommierten Fachzeitschrift „Cell“ stellt einen wichtigen Meilenstein auf dem Weg zur klinischen Anwendung dar und zielt darauf ab, die Gesundheitsspanne der Menschen deutlich zu verlängern. Das BOKU-Spin-off Rockfish Bio plant, diese vielversprechenden Forschungsergebnisse in konkrete therapeutische Ansätze zu überführen. ℹ️ https://lnkd.in/guN9-DJD

University of Natural Resources and Life Sciences, Vienna (BOKU)

Dear Olga, thank you for your comprehensive summary of our talk! It is great to be here in Berlin and to be able to present our newest data on the rejuvenating effect of our lead compound in front of such a well educated audience.

Meet us at the Rejuvenation Startup Summit 2024! I am happy to announce that our CEO Otto Kanzler was invited to present our company at this exciting event, where investors can meet the leaders of the rejuvenation biotech industry. https://lnkd.in/gJYzViw7

Read more about our latest successes and plans in this year's startupreport.at/get23 It is inspiring to read about the progress, funding successes and innovations of so many Austrian startups. Thanks Dr. Florian Kandler and the Startup Report team for promoting entrepreneurship and innovation this way. We are glad to be part of this initiative!

Could "old" become the new "sexy"? Our senolytic lead compound improves not only the health and life span but also the looks of our mice. If you are interested in joining our series A funding, please get in touch with us!

Excellent data from PoC study with our senolytic lead molecule RFB01016! Our newest data shows a massive extension of health span (frailty index) and life span (+40 % of median survival time), as well as improvements in neuromuscular function and reduction of senescent cells in several tissues (kidney, liver, brain, spleen, fat, ...). We are currently seeking funding, so don't miss this opportunity and get in touch with us!

Austria Companies (Top 10K)

Life Science Companies With Fewer Than 1000 Employees

European Union (EU) Life Science Companies

Europe, Middle East, and Africa (EMEA) Clinical Trials Companies

Rockfish Bio is a biotechnology company focused on developing senolytic compounds aimed at promoting healthy aging. The company leverages a newly discovered target pathway to create innovative treatments that improve the quality of life. With a team of experts in aging research, Rockfish Bio is dedicated to advancing scientific understanding and therapeutic options in the field of healthy aging.

Vienna

Wien

Austria

Europe

Therapies targeting age-related diseases such as chronic kidney disease, liver fibrosis, pulmonary fibrosis, neurodegenerative diseases, frailty, sarcopenia, and osteoarthritis.

Senolytic therapies using mRNA technology for various unspecified applications.

A lead compound that extends health and lifespan, improves neuromuscular function, and reduces senescent cells in multiple tissues.

Mexico

North America

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Rockfish Bio