Inscopix, Inc. provides pioneering neural circuit imaging solutions to improve understanding of the brain and accelerate therapeutic development for neurological and psychiatric disorders.

Inscopix, Inc.

Inscopix, Inc. | 5,425 followers on LinkedIn. A New Approach to Understanding and Healing the Brain | Inscopix is pioneering a new paradigm in the quest to understand the brain and its diseases. Combining revolutionary technology and methods for the imaging of large-scale neural activity in a naturally behaving subject, Inscopix has developed the enabling means to relate causal neural circuit dynamics to corresponding behavior. With its nVista and nVoke products, Inscopix is today disseminating these capabilities to neuroscientists across the world, empowering them to gather unprecedented data and to make new scientific discoveries.

Sales Representative chez Inscopix, Inc.

Nicolas Bonneau

Neuroscientist, Regional Sales Manager at Inscopix, Inc.

Fabio Cacciapaglia, PhD

Imaging Expert • Scientific Consultant • Neuroscientist • Data Analyst

Qing Liu

Product Manager at Inscopix, Inc.

Brice Tiret

Can’t believe #SfN24 was almost a month ago! We’re still buzzing from the fascinating conversations and innovations in neuroscience we encountered. 🧠 If you missed the action or want to relive it, check out our #SfN2024 recap by Bruker Life Science Writer 𝗠𝗲𝗹𝗶𝘀𝘀𝗮 𝗠𝗮𝗿𝘁𝗶𝗻, where she captures the energy and insights that made this year unforgettable! https://hubs.ly/Q02XdmdH0

Ever wondered what drives an aggressive state in the brain? 𝗚𝗲𝗼𝗿𝗴𝗲 𝗠𝗼𝘂𝗻𝘁𝗼𝘂𝗳𝗮𝗿𝗶𝘀 et al. from 𝗗𝗮𝘃𝗶𝗱 𝗝. 𝗔𝗻𝗱𝗲𝗿𝘀𝗼𝗻's lab at Caltech has some fascinating answers! Published in Cell, this study uncovers how neuropeptide signaling in the hypothalamus shapes aggression. 𝗞𝗲𝘆 𝗙𝗶𝗻𝗱𝗶𝗻𝗴𝘀: ✔️This work shows that 𝗼𝘅𝘆𝘁𝗼𝗰𝗶𝗻 and 𝘃𝗮𝘀𝗼𝗽𝗿𝗲𝘀𝘀𝗶𝗻 𝗿𝗲𝗰𝗲𝗽𝘁𝗼𝗿𝘀 in the VMH encodes a sustained state of aggression. ✔️Employing "𝗖𝗥𝗜𝗦𝗣𝗥𝗼𝘀𝗰𝗼𝗽𝘆," which combines CRISPR gene editing and 𝘀𝗶𝗻𝗴𝗹𝗲-𝗰𝗲𝗹𝗹 𝗰𝗮𝗹𝗰𝗶𝘂𝗺 𝗶𝗺𝗮𝗴𝗶𝗻𝗴 with #𝗻𝗩𝗶𝘀𝘁𝗮 , the study pinpointed how disrupting neuropeptide receptors reduces aggressive behavior without altering other social responses. ✔️The study highlights unique "𝗹𝗶𝗻𝗲 𝗮𝘁𝘁𝗿𝗮𝗰𝘁𝗼𝗿 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀," where neural circuits actively maintain internal states like aggression, driven by neuropeptide signaling. This research is a leap toward understanding how internal states are encoded and maintained in the brain! ➡️ https://hubs.ly/Q02WFgMr0

🌐Register for our New Horizons webinar with Dr. Matsuda from Gifu University as he presents his #nVoke optogenetics & imaging research. Gain valuable insights into essential fluid regulation of salt & water, crucial appetitive processes. Secure your spot! https://hubs.ly/Q02VHk000

🚨 New Insights into 𝗦𝗼𝗰𝗶𝗮𝗹 𝗙𝗲𝗮𝗿 𝗣𝗿𝗼𝗰𝗲𝘀𝘀𝗶𝗻𝗴 from Columbia's Mortimer B. Zuckerman Mind Brain Behavior Institute ! Pegah Kassraian and the team from Dr. Steven A. Siegelbaum lab at Columbia University have uncovered new insights into how the hippocampus processes social fear. By employing advanced techniques such as 𝘀𝗶𝗻𝗴𝗹𝗲-𝗰𝗲𝗹𝗹 𝗰𝗮𝗹𝗰𝗶𝘂𝗺 𝗶𝗺𝗮𝗴𝗶𝗻𝗴 𝘄𝗶𝘁𝗵 𝗜𝗻𝘀𝗰𝗼𝗽𝗶𝘅'𝘀 #𝗻𝗩𝗶𝘀𝘁𝗮 , they revealed the critical roles of the CA2 and CA1 regions in distinguishing social threats from safety. Their study, published in 𝗡𝗮𝘁𝘂𝗿𝗲 𝗡𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲, reveals that: 𝗗𝗶𝘀𝘁𝗶𝗻𝗰𝘁 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻𝘀: 🧠𝗖𝗔𝟮 distinguishes between safe and threatening social interactions. 🧠𝗖𝗔𝟭 encodes the locations tied to these experiences. 𝗘𝘅𝗽𝗲𝗿𝗶𝗺𝗲𝗻𝘁 𝗿𝗲𝘀𝘂𝗹𝘁𝘀: Mice learned to avoid a "risky" stranger associated with a mild shock. ✳️𝗦𝗶𝗹𝗲𝗻𝗰𝗶𝗻𝗴 𝗖𝗔𝟭 caused mice to forget the shock location. 🐁𝗦𝗶𝗹𝗲𝗻𝗰𝗶𝗻𝗴 𝗖𝗔𝟮 made mice fearful of both strangers—pointing to a connection with generalized social avoidance, a core feature of social anxiety and related disorders. 💡These findings highlight 𝗖𝗔𝟮’𝘀 𝗿𝗼𝗹𝗲 in regulating 𝘀𝗼𝗰𝗶𝗮𝗹 𝗳𝗲𝗮𝗿 𝗺𝗲𝗺𝗼𝗿𝘆, a process vital for survival, opening new paths for understanding conditions like PTSD and social anxiety. Fantastic Research. Read for more insight 🡪 https://hubs.ly/Q02VS-3j0

🌐Join our New Horizons webinar with the esteemed Dr. Takashi Matsuda from Gifu University as he shares his latest insights using optogenetic manipulation and calcium imaging with the #nVoke system. Discover how the brain monitors body fluids like salt & water - critical appetitive processes! Register here to learn more👇 https://hubs.ly/Q02VHp_b0

🧠🔬 The 𝗜𝗻𝘀𝗰𝗼𝗽𝗶𝘅 𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 𝗟𝗮𝗯 showcased a wide range of groundbreaking research at #SfN24 , and now you can access it all! From 𝗺𝗶𝗻𝗶𝘀𝗰𝗼𝗽𝗲-𝗯𝗮𝘀𝗲𝗱 𝗯𝗹𝗼𝗼𝗱 𝘃𝗲𝘀𝘀𝗲𝗹 𝗶𝗺𝗮𝗴𝗶𝗻𝗴 for migraine therapeutics to 𝗻𝗲𝘂𝗿𝗼𝗯𝗲𝗵𝗮𝘃𝗶𝗼𝗿𝗮𝗹 𝗽𝗿𝗼𝗳𝗶𝗹𝗶𝗻𝗴 for antidepressants and antipsychotics, their posters cover key advancements in neuroscience drug development and therapeutic assessment. You can now download these presentations and explore the details on our 𝗻𝗲𝘄 𝘄𝗲𝗯𝘀𝗶𝘁𝗲, including information about their 𝗖𝗥𝗢 𝘀𝗲𝗿𝘃𝗶𝗰𝗲𝘀 advancing preclinical research! Check it out here ➡️ https://hubs.ly/Q02TsXtd0 #CROServices #Preclinical #Neuroscience #DrugDevelopment #InscopixDiscoveryLab

🌍 Today is 𝗪𝗼𝗿𝗹𝗱 𝗠𝗲𝗻𝘁𝗮𝗹 𝗛𝗲𝗮𝗹𝘁𝗵 𝗗𝗮𝘆, and this year’s theme, "𝗠𝗲𝗻𝘁𝗮𝗹 𝗛𝗲𝗮𝗹𝘁𝗵 𝗮𝘁 𝗪𝗼𝗿𝗸" reminds us of the power of understanding the brain and its impact on our well-being. Let’s continue to push boundaries in neuroscience while creating workplace cultures that value mental health. A healthy mind leads to groundbreaking ideas and discoveries.

🌟 #𝗦𝗳𝗡𝟮𝟰 , Society for Neuroscience 𝟮𝟬𝟮𝟰, 𝗵𝗮𝘀 𝗰𝗼𝗺𝗲 𝘁𝗼 𝗮 𝗰𝗹𝗼𝘀𝗲, 𝗮𝗻𝗱 𝗼𝘂𝗿 𝗵𝗲𝗮𝗿𝘁𝘀 𝗮𝗿𝗲 𝗳𝘂𝗹𝗹! To the #𝗜𝗻𝘀𝗰𝗼𝗽𝗶𝘅 𝗰𝗼𝗺𝗺𝘂𝗻𝗶𝘁𝘆, thank you for driving the remarkable research that fuels innovation. We’re grateful to everyone who visited our booth, shared inspiring conversations, and engaged with the work of our amazing customers. And a special thank you to the Inscopix, Inc. & Bruker team — your energy and dedication made it all happen! Excited for what’s next -- let’s keep advancing neuroscience together!

⏳𝗟𝗮𝘀𝘁 𝗽𝗼𝘀𝘁𝗲𝗿 𝘀𝗲𝘀𝘀𝗶𝗼𝗻 𝗼𝗳 #𝗦𝗳𝗡𝟮𝟰 , 𝗯𝘂𝘁 𝘁𝗵𝗲 𝗲𝘅𝗰𝗶𝘁𝗲𝗺𝗲𝗻𝘁 𝗶𝘀𝗻’𝘁 𝗼𝘃𝗲𝗿 𝘆𝗲𝘁! Don’t miss 𝗧𝗶𝗻𝗮 𝗠𝗮𝗵𝗺𝗼𝘂𝗱𝗶's presentation from Bruker , featuring the powerful Quartet #miniscope . This innovative multi-region miniscope allows for recording neural activity in four brain regions simultaneously—yes, four! Get valuable insights into brain circuits during behaviors like open-field exploration and swimming! 📅 Wednesday, October 9 | 1:00PM - 5:00PM 📍 PSTR491.08 / X33 ➡️ https://hubs.ly/Q02SJs8W0

Last day at #SfN24 and there’s so much to see, learn, and explore! Be sure to check out Tamás Füzesi from the Jaideep Bains Lab at the University of Calgary as they present research on how CRH neurons in the hypothalamus anticipate potential threats. Using #miniscope imaging, they reveal new insights into stress responses and neuropsychiatric disorders. Check it out: https://hubs.ly/Q02SJrMY0

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